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International Journal of Respiratory Medicine
|
Volume 3
LUNG CANCER AND COPD
5
th
International Congress on
J u n e 2 5 - 2 6 , 2 0 1 8 | A m s t e r d a m , N e t h e r l a n d s
Wassil Nowicky, Int J Respir Med 2018, Volume 3
EFFECTS OF THE ANTI-CANCER
PREPARATION NSC-631570
(UKRAINE) ON LUNG CANCER
Wassil Nowicky
Nowicky Pharma, Austria
C
linical efficacy of NSC‐631570 is not coincidental or even ‘spontaneous
remission’ but rather a consequence of its mechanisms of action
confirmed in various
in vitro
and
in vivo
studies. NSC‐631570 has been tested
on more than 100 cancer cell lines so far. Among others, NSC‐631570 was
tested at the National Cancer Institute (Bethesda, Maryland, USA) on 60 cell
lines representing eight important human malignant tumors: brain tumors,
ovarian, small cell and non‐small lung cancer, colon cancer, kidney cancer,
leukaemia and malignant melanoma. NSC‐631570 exerted toxic effects
against all these cell lines. Compared to 5‐fluorouracil (5‐FU) and gemcitabine,
two standard cytotoxic agents in the treatment of digestive tract tumors,
NSC‐631570 achieved better results and not only inhibited the cell growth but
reduced the cell mass, also. In 1998, a group around Anne Panzer (University
of Pretoria, South Africa) proved the selective effect of NSC‐631570 on
molecular level. Tests on human cervical carcinoma cells HeLa, squamous
cell carcinoma WHCO5 and normal equine lung cell lines demonstrated that
NSC‐631570 is selectively toxic against cancer cells. It causes a metaphase
block which is characterized by an abnormal distribution of chromosomes
and the formation of micronuclei and results in apoptosis. Normal cells are
not influenced in the process. NSC‐631570 was effective in the therapy of
recurring lung diseases in children from the Chernobyl area.
Wassil Nowicky is the President of the Ukrainian
Anti-Cancer Institute (Vienna, Austria). He has
finished his study as the Radio Technical Fac-
ulty in the Technical University of Lviv (Ukrainee)
in the end of 1955. He was the author of over
300 scientific articles dedicated to cancer re-
search. He is a real member of the New York
Academy of Sciences, member of the European
Union for applied immunology and of the Amer-
ican Association for scientific progress. He has
received the award for merits of National Guild
of Pharmacists of America, the award of Aus-
trian Society of Sanitary, Hygiene and Public
Health Services and others.
dr.nowicky@yahoo.deBIOGRAPHY
UKRAINE concentration