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International Journal of Respiratory Medicine

|

Volume 3

LUNG CANCER AND COPD

5

th

International Congress on

J u n e 2 5 - 2 6 , 2 0 1 8 | A m s t e r d a m , N e t h e r l a n d s

Marousa Kouvela, Int J Respir Med 2018, Volume 3

THE ROLE OF DOUBLE

BRONCHODILATION IN COPD

TREATMENT

Marousa Kouvela

Boehringer-Ingelheim, Greece

B

ronchodilators play a central role in COPD treatment. At the end of the

previous year, the GOLD (Global Initiative for Global Obstructive Lung

Disease) strategy for the diagnosis, management and prevention of COPD

has been updated and published with several changes. One of the most

important changes was the shift of the treatment recommendations toward

the maximization of bronchodialative therapy to all COPD patients and the

restriction of ICS use to more specific patient groups, although, the ICS

overuse continues to be an issue to many countries worldwide. The direct

comparison of inhaled LABA/LAMA combinations to the nanocomponents or

a LABA/ICS combination shows superiority of the LABA/LAMA combination

in case of lung function, symptoms and quality of life. Recently, there has

been a question whether a LABA/LAMA combination is equally or even

more efficient than a LABA/ICS combination therapy in the prevention of

COPD exacerbations. Another question that needs to be clarified is how

safe is to withdraw ICS from the patients that do not need them and how

this is applicable in everyday clinical practice. It seems that a LABA/LAMA

combination is very efficient and safe treatment option to all COPD groups

and it should be applied from the beginning of COPD treatment. The efficacy

of the double bronchodilation is mainly attributed to the reduction of the

lung hyperinflation, the enhancement of mucociliary clearance and their

anti-inflammatory properties. Moreover, it seems that the simultaneous

administration of two bronchodilators offers a synergic action to the lungs.

Marousa Kouvela is a pulmonologist. She has

completed her residency in one of the largest

general hospitals in Greece and achieved her

specialty board degree in 2013. She has com-

pleted her Master of Science in Thoracic On-

cology. She has participated in many national

and international scientific and educational

seminars and published in national and inter-

national journals. Her special scientific interests

are COPD, lung cancer and interventional pulm-

onology. She is currently working as a Medical

Manager in Boehringer Ingelheim Ellas, Greece.

markouvela@yahoo.gr

BIOGRAPHY