liver-2018-posters-accepted-abstracts

Page 49

allied

academies

Journal of Gastroenterology and Digestive Diseases | Volume 3

May 25-26, 2018 | New York, USA

World Liver Conference 2018

Background:

Liver resection is the only viable therapeutic

treatment option for several neoplastic entities of the liver.

Although, the number of resectable patients is increasing

in Syria, liver failure is still a major complication affecting

mortality and morbidity rates. Methods: Between 2009 and

2016, 104 patients undergoing liver resection in Damascus

University Faculty of Medicine were retrospectively

analyzed. Liver function tests were conducted before

surgery (ps) and in the perioperative period (po) and

comparisons were performed with division into anatomic

VS non-anatomic or malignant VS non-malignant groups.

Results: Liver synthetic, excretory and detoxifying functions

deteriorated after liver resection (INR ps ‘presurgery’=1.129

po ‘perioperative’=1.426 P<0.001, TP ps=7.426 po=5.581

P<0.001, ALB ps=4.204 po=3.242 P<0.001, T-Bill ps=0.061

po=0.136 P<0.001) and liver cell necrosis increased after

resection (ALT ps=27.597 po=200.221 P<0.001, AST

ps=33.395 po=190.553 P<0.001). There was no significant

difference in liver functions when we compared anatomic

VS non-anatomic groups or malignant VS non-malignant

groups, but liver cell necrosis was higher with malignancies

(ALT malignant group=236.475 non-malignant group=89.5

P=0.002, AST malignant group=222.644 non-malignant

group=101.125 P=0.001). Conclusion: Although liver

resection affects liver function significantly, no differences in

outcomes were found between anatomic VS non anatomic

or malignant VS non-malignant groups.

Perioperative liver function after hepatectomy in a tertiary university hospital in Damascus

Basel Ahmad, Khaled Turkmani, Mohamad Essam Marwa, Tareq Ahmad, Ramez Baghdadi, Shaimaa Aboudamaah, Khetam Alkhatib

and

Mohamad

Ahmad

Damascus University, Syria