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Virology Research Journal

|

Volume 2

Page 26

Note:

allied

academies

IMMUNOLOGY AND CELL BIOLOGY

BACTERIOLOGY AND INFECTIOUS DISEASES

&

Global Summit on

Global Congress on

J u n e 2 5 - 2 6 , 2 0 1 8 | A m s t e r d a m , N e t h e r l a n d s

Joint Event on

A CLUSTER-RANDOMIZED

CONTROLLED TRIAL TO DECREASE

HAND, FOOT AND MOUTH DISEASES

IN CHINESE KINDERGARTENS: THE

CLEAN HANDS, HAPPY LIFE PROGRAM

Xiaona Liu

University Medical Center Rotterdam, Netherlands

Objectives:

To evaluate the effect of the clean hands, happy life intervention

on the incidence of hand, food and mouth disease (HFMD) and on school

absences due to sickness in kindergarten students.

Methods:

The intervention consisted of four hand hygiene (HH) promotion

components andwas evaluated ina cluster-randomized controlled trial among

8275 children and 18 kindergartens from May to October, 2015 in Shenzhen,

China. We compared two intervention arms - received the intervention in

kindergartens only and in both kindergartens and families, respectively - to

the control arm that continued usual practice.

Results:

During the follow-up, the incidence of HFMD in both intervention

arms was significantly lower than in the control arm (IRR1: 0.40, 95% CI: 0.26-

0.62; IRR2: 0.35, 95% CI: 0.22-0.57); the duration of absence due to sickness

in both intervention arms was significantly shorter than in the control arm

(β1=0.58, 95% CI: 0.41-0.74; β2=0.34, 95% CI: 0.17-0.50), controlling for the

area type of kindergarten and grade level of children. Furthermore, during

the follow-up we found that there were fewer episodes of absence due to

respiratory, skin and eye infections (P<0.05).

Conclusions:

Our intervention is effective at reducing HFMD infections and

absence due to sickness in children attending kindergartens in China.

Xiaona Liu is a Postdoc Researcher at the De-

partment of Public Health, University Medical

Center in the Netherlands. She holds two re-

search master degrees and one doctoral de-

gree in Public Health and Infectious Disease

Control. She is specialized in the development

and evaluation of public health interventions for

preventing diseases (both communicable and

non-communicable), combing with strong in-

terests in behavioral change techniques, health

psychology, and implementing research find-

ings into practice. Her work currently involves

Dutch-China joint research on hand hygiene im-

provement, as well as evaluation of the imple-

mentation of preventive programs at different

clinical wards of the Erasmus Hospital in Rotter-

dam, the Netherlands.

x.liu@erasmusmc.nl

BIOGRAPHY

Xiaona Liu, Virol Res J 2018, Volume 2