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Curr Trend Cardiol. 2017 | Volume 1 Issue 3
September 18-19, 2017 | Toronto, Canada
Annual Conference on
HEART DISEASES
A
70-year-old male complained exertional dyspnea. Chest
X-ray and computed tomographic scanning showed left
pleural effusion. Diuretic and antibacterial therapy started
but his pleural effusion remained. Biopsy by videoassisted
thoracoscopic surgery was performed, and its pathological
fingings showed deposition of amyloid protein at alveolar
walls and vascular walls in left upper lung. So, he was
diagnosed as localized pulmonary amyloidosis at first. After
three months, he complained recurrence of exertional
dyspnea and leg edema. Chest X-ray computed tomographic
scanning showed bilateral pleural effusion. Ultrasound
cardiography showed left ventricular dysfunction and
hypertrophy. So, he was considered as complicating cardiac
amyloidosis. Althrough cardiac biopsy didn’t show amyloid
protein, clinical fingings such as left ventricular hypertrophy
consistent with cardiac amyloidosis. In addition, upper
gastrointestinal tract biopsy also showed amyloid protein,
so he was diagnosed as systemic amyloidosis including
cardiac symptoms. Bone marrow biopsy performed in order
to identify the underlying disease of systemic amyloidosis
showed abnormal plasma cells, so hewas finally diagnosed as
multiple myeloma that caused systemic amyloidosis. In this
seminar, I will show this rare case report in that pulmonary
amyloidosis preceded other organs in systemic amyloidosis.
We firstly diagnosed as localized lung amyloidosis, but
after cardiac failure combined we finaly could diagnosed as
systemic amyloidosis with multiple myeloma.
Speaker Biography
Mitsutaka Nakashima is an expert in the diagnosis and treatment of cardiovascular
diseases, including hypertension, dyslipidemia, atherosclerosis, peripheral arterial
disease, coronary artery disease, arrythmia and pulmonary hypertension. He
graduated Okayama University Medical School in 2013. He subsequently completed
his residency of cardiology at Hiroshima City Hospital and Okayama Medical Center. He
is currently the staff of Dep. Of Cardiovascular medicine at Iwakuni Clinical Hospital,
Yamaguchi, Japan. His clinical interests include the diagnosis and treatment of heart
failure and pulmonary hypertension.
e:
mitsn1023@gmail.comA case of systemic amyloidosiswithmultiplemyeloma proceededby pulmonary amyloidosis diagnosed
after developing cardiac failure with cardiac amyloidosis
Mitsutaka Nakashima
Iwakuni Clinical Center, Japan