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academies
March 07-09, 2019 | London, UK
2
nd
International Conference on
7
th
International Conference on
Food Safety and Hygiene
Nutrition, Food Science and Technology
Joint Event
&
Journal of Food Technology and Preservation | Volume 3
Severe combined immune deficiency and continued breastfeeding: Report of 5 own mother’s milk
donation (OMM) at the regional Ile de France milk bank
Virginie Rigourd
Human Milk Bank, France
Introduction:
Severe Combined Immunodeficiency (SCID), is
a group of rare inherited diseases characterized by the severe
impairment or even absence of both cellular and humoral
immunity. Thus, children with SCID are immune-compromised,
which render them easily susceptible to opportunistic and
lethal infections, including various bacteria and viruses,
especially Cyto-Megalo Virus (CMV), that may be transmitted
by their mothers’ milk during breastfeeding. Therefore, CMV
seropositive mothers are forced to discontinue breastfeeding,
and switch to formula feeding, soon after their children are
diagnosed with SCID disease. However, in addition to the
allogeneic stem cell transplant and gene therapy, breastfeeding
can also be a natural mean of protection against secondary
infections in addition to its nutritional benefits. Therefore, we
provide a simple and available technique to maintain mothers’
milk feeding for children with SCID even for CMV seropositive
mothers.
Study design:
Between May 2013 and August 2014, the
regional IDF milk bank has pasteurized 5 milk samples of CMV
seropositive mothers, whose children were placed in a sterile
room.
The Holder pasteurization (30 min at 62,5°C) and the
bacteriologic milk analysis were conducted, following the 2008
good practices guide of themilk bank. A virological CMV analysis
was also made on these milk samples.
Results:
The milk delivered was bacteriologically-proven to
be sterile and CMV negative. All 5 infants received their own
mother’s milk during their isolated period. Breastfeeding was
continued even after their discharge home.
Discussion:
All CMV seropositive mothers (50% of women in
France) excreteCMV in theirmilk. Unlike freezing, pasteurization
is the best way to stamp out CMV in human milk samples.
Conclusion: Thus, the contribution of milk banks should be
more and more requested for promoting breastfeeding and
favoring the mother-child bond especially in case of severe
combined immune deficiency.
Speaker Biography
Virginie Rigourd is the managing director of the Human Milk Bank of Ile de France. She
has graduated from the Medicine University in Paris, France in 1998 and finished post
graduate training in 2003 from the same university on intra uterin growth retardation
topics. She worked as paediatrician ahead of Ile de France Milk Bank, Paris, France
and neonatalogiste in NICU at Necker Hospital, Paris, France. Member of the French
Milk Bank Association and European Milk Bank Association. Since 2002 she worked as
a national consultant, providing assessments of human milk security and on projects
on human milk quality. Dr. Rigourd has carried out few researches on medication and
breast feeding. During her work she has gained local and national recognition for
her different advice on breast feeding and on practice around human milk in NICIU.
e:
virginie.rigourd@nck.aphp.frVirginie Rigourd
, J Food Technol Pres, Volume 3
DOI: 10.4066/2591-796X-C1-005