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Note:
allied
academies
J u n e 2 8 - 2 9 , 2 0 1 8 | A m s t e r d a m , N e t h e r l a n d s
Joint Event on
OBESITY AND WEIGHT MANAGEMENT
VACCINES AND IMMUNOLOGY
&
International Conference on
International Conference on
Asian Journal of Biomedical and Pharmaceutical Sciences
|
Volume 8
ISSN:
2249-622X
SHORT-TERM CHANGES IN
CARDIOVASCULAR HEMODYNAMICS
IN RESPONSE TO BARIATRIC
SURGERY AND WEIGHT LOSS USING
THE NEXFIN® NON-INVASIVE
CONTINUOUS MONITORING DEVICE
Sjaak Pouwels
Franciscus Gasthuis & Vlietland, Netherlands
Background:
Compared to healthy individuals, obese patients have
significantly higher systolic and diastolic blood pressure; mean arterial
pressure, heart rate and cardiac output. The aim of this study was to evaluate
cardiovascular hemodynamic changes before and three months after
bariatric surgery.
Methods:
Patients scheduled for bariatric surgery between the 29
th
of
September 2016 and the 24
th
of March 2016 were included and compared
with 24 healthy individuals. Hemodynamic measurements were performed
preoperatively and threemonths after surgery, using the Nexfin®non-invasive
continuous hemodynamic monitoring device.
Results:
80 subjects were included in this study, respectively 56 obese
patients scheduled for bariatric surgery and 24 healthy individuals. Baseline
hemodynamic measurements showed significant differences in cardiac
output (6.5±1.6 versus 5.7±1.6 l/min, p=0.046), mean arterial pressure
(107±19 versus 89±11 mmHg, p=0.001), systolic (134±24 versus 116±18
mmHg, p=0.001) and diastolic blood pressure (89±17 versus 74±10 mmHg,
p=0.001) and heart rate (87±12 versus 76±14 bpm, p=0.02) between obese
and healthy subjects. Three months after surgery, significant changes
occurred in mean arterial pressure (89±17 mmHg, p=0.001), systolic (117±24
mmHg, p=0.001) and diastolic blood pressure (71±15 mmHg, p=0.001),
stroke volume (82.2±22.4 ml, p=0.03) and heart rate (79±17 bpm, p=0.02)
Conclusion:
Three months after bariatric surgery significant improvements
occur in hemodynamic variables except cardiac output and cardiac index, in
the patient group.
Sjaak Pouwels is a MD, PhD holder and a sur-
gical resident, currently working at the Depart-
ment of Surgery, Franciscus Gasthuis and Vliet-
land in Rotterdam, Netherlands. He is interest-
ed in the broad spectrum of obesity research;
mainly effects of bariatric surgery and physio-
logical changes due to obesity. His recent re-
search focused on cardiovascular hemodynam-
ic changes and remission of type 2 diabetes
mellitus after bariatric and metabolic.
surgery.sjaakpwls@gmail.comBIOGRAPHY
Sjaak Pouwels, Asian J Biomed Pharmaceut Sci 2018, Volume 8 | DOI: 10.4066/2249-622X-C1-002