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Journal of Clinical and Experimental Toxicology | Volume: 3
February 21-22, 2019 | Paris, France
International Conference on
Environmental Toxicology and Pharmacology
Safety and efficacy of current emerging systemic therapies in Melanoma associated Tumours
Mihai-Andrei Iordache
University of Medicine and Pharmacy, Romania
M
elanoma tumours dissemination is the most frequent
complication of skin cancer. New advances of
technologies provide new tools for understanding and limit
dissemination of malignant cells, but only limited studies was
focused on brainmetastases. One of themajor obstacle in brain
tumor prevention associated with malign melanoma is the
genetic heterogenity of the malignant cell. These cells display a
key molecular supportive changes and targeting these changes
we can develop safe and efficient strategies. In this study
summarize the safety and efficacy of current emerging systemic
therapies, especially targeted therapies and immunotherapies,
for the treatment of central nervous system tumors, focusing on
melanoma. The aim is to create a complete image regarding the
therapeutic options available in order to imlement personalized
treatment for these patients.
Speaker Biography
Mihai-Andrei Iordache was born on November 19, 1944. He received the M.S. and
Ph.D. degrees in Electrical Engineering from the Politehnica University of Bucharest,
Romania, in 1967 and 1977, respectively. From 1993 he is a Full Professor in the
Electrical Department, Politehnica University of Bucharest, where he is working
in the Electrical Engineering Fundamentals, Circuit Theory – methods, computing
techniques, algorithms, optimization techniques, parameter estimations, and software
tools for analysis and simulation, Graph Theory, Wireless Power Transfer Systems, and
Topological Analysis. He is the author or coauthor of more than 300 journal papers
(two of them published in Analog Integrated Circuits and Signal Processing, and in
International Journal of Bifurcation and Chaos) and 30 books and monographs. From
1997 he is Doctoral Advisor at the Politehnica University of Bucharest. He was the
recipient of the 2000 Romanian Academy Award and of the 2004 Romania Engineering
Association. He is an IEEE member.
e:
mihai.andrei.iordache@gmail.comMihai-Andrei Iordache, J Clin Exp Tox, Volume 3
DOI: 10.4066/2630-4570-C1-006