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Res Rep Gynaecol Obstet 2017 | Volume 1 Issue 4
November 02-03, 2017 | Chicago, USA
Embryology and In vitro Fertilization
World Congress on
The role of microorganisms in steroidal hormones transformation
Bushra Abdul-Hadi
1
and
Mohammad Yasin Mohammad
2
1
Al-Ahliyya Amman University, Jordan
2
Middle East University, Jordan
B
iocatalysis concept is based on the use of biological
catalysts (enzymes, living organisms and cells) to
perform chemical conversions on organic compounds.
Biotransformations have been applied for the conversion
of a variety of organic compounds, especially steroidal and
terpenoidal compounds, since it is difficult to carry out direct
chemical changes on unreactive carbon centers of steroidal
molecules by conventional chemical reactions. Steroids are
generally present in animals, plants and fungi. All steroids
that are found in animals and fungi are biosynthesized from
the lanosterol.While those found in plants are biosynthesized
from the cycloartenol. Both lanosterol and cycloartenol are
derivatives of a triterpene squalene. Microorganisms have
been used extensively for the transformation of steroids and
particularly steroidal hormones since their enzymes catalyze
reactions with high regio- and stereospecifity. In this study,
microbial transformations of steroidal hormones have been
compiled and covered
Speaker Biography
Bushra Abdul-Hadi has obtained her PhD degree (Therapeutics and Clinical Pharmacy)
in 2012 from Hungary. She is currently working as an Assistant Professor at the Faculty
of Pharmacy and Medical Sciences, Al-Ahliyya Amman University, Amman, Jordan. She
wishes to contribute in raising standards of education and research in Jordan.
e:
Bushra_abdul@yahoo.com