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Page 38
allied
academies
August 16-17, 2018 | Copenhagen, Denmark
Dementia and Alzheimer ’s Disease
10
th
World congress on
Journal of Neurology and Neurorehabilitation Research | Volume: 3
Alzheimer’s cognitive impairment can be recovered by decreasing homocysteic acid in blood
Tohru Hasegawa
Saga Woman Junior College, Japan
R
ecent big two clinical trials of amyloid beta treatment for
Alzheimer’s disease are all failed to recover the cognitive
impairment, it has forced us to reconsider the central
hypothesis of amyloid pathogen for Alzheimer’s disease.
We recently published that human Alzheimer’s patients
showed the strong relationship between Mini Mental State
Examination (MMSE) scores and blood homocysteic acid (HA)
level. 6 AD patients (all female: age 77, 82, 86, 87, 91, 91)
were given green tea powder 1g at every meal for 2 months.
Their blood HA level and MMSE score were measured
before and after taking green tea powder. The relationship
between blood HA level change and MMSE score change
was investigated. The strong statistically significant negative
relationship between blood HA level change andMMSE score
change: r=-0.96, p=0.00018, n=6. From our observation, it
showed that blood HA level change induced MMSE score
change, that is, Alzheimer’s cognitive ability was controlled
by blood HA level. Now we can present that some healthy
food, that is named HBF, can recovered 100% Alzheimer’s
cognitive impairment by the decreasing the homocysteic
acid in a peripheral blood. Now we have made a relative
large open trial of AD patients. 91 patients were enrolled.
Their cognitive recovery was measured by NM scale (New
Clinical Scale for Rating of Mental States). All patients who
took HBF showed the recovery of their behaviors. From this
open-trial of HBF, (1) Alzheimer’s cognitive impairment could
be recovered at even end stage. (2) Alzheimer’s disease is
induced by homocysteic acid.
e
:
tohru.hasegawa@pharm.jp