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May 13-14, 2019 | Prague, Czech Republic
Chemistry and Medicinal Chemistry
9th World Congress on
Asian Journal of Biomedical and Pharmaceutical Sciences | Volume 9 ISSN: 2249-622X
Bioinspired membrane systems state-of-the art and innovative solution to overcome
main limits
Rosalinda Mazzei
National Research Council of Italy, Italy
Nanostructured microporous membranes functionalized
with biomolecules are very suitable for the development
of biohybrid and biomimetic systems which find application
in various fields including biocatalysis, biomedicine and
biotechnology. The system simulates the biological membrane
environmental like, where the biological system can be
heterogenized inside/on the membrane and its passage can
be regulated by controlled fluid dynamic conditions. Despite
the advantages of nature simulation by bio-inspired materials
application, there are some issues which need to be addressed
in order to achieve the development of such systems. Themain
problems are related to both biomolecule stability as well as
membrane cleaning and re-use.
Analyzing the use of membrane bioreactor (MBR) technology
in patents development as well as their industrial application, it
seems that themajor development has been obtained byMBR
for water treatment, whilst lower efforts have been devoted to
MBR for pharmaceutical, food, cosmetics, etc. This is mainly
due to more strict regulations that govern the discharge of
waste water into the environment. However, the need to
promote more sustainable processes for industrial production
will force thedevelopment ofMBRalso inother fields, including
biorefinery for bioderived chemicals.
In this work, alternative strategies to solve problems related
to membrane stability/enzyme re-use will be described (e.g.
the use of biofunctionalized nanoparticles integrated with
membrane process). A deep understanding of biomolecule
immobilization on membrane will be illustrated by using
different biomolecule and functionalized membranes, to proof
the concept of membrane versatility. In addition a biocatalytic
multiphasic intensified membrane system, able produce and
compartmentalize poor water stable antioxidant molecules will
be also described, with the aimto provide alternative strategies
for process intensification.
Speaker Biography
Rosalinda Mazzei received her PhD from University of Calabria (UNICAL)
in 2009 and she is currently a researcher of the Institute on Membrane
Technology since 2011. Her expertise is in the development of biohybrid
membrane process for catalysis, integrated membrane process and
in process intensification. She won different prizes in international
conferences and she has recently started to collaborate with different
Universities such as Leuven (Belgium), University of Federico Santa Maria
(Chile), School of food Engineering Pontificia, Universidad Catolica de
Valparaìso (Chile), Universidad Industrial de Santander (Colombia) etc.
She published about 50 articles on international journal and more than
10 chapters on books.
e:
Rosalinda Mazzei, Asian J Biomed Pharmaceut Sci, Volume:9
DOI: 10.4066/2249-622X-C2-020
Notes: