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academies
Journal of Medical Oncology and Therapeutics | Volume: 3
July 23-25, 2018 | Moscow, Russia
12
th
World Cancer Congress
Proposal of a Nutritional Screening for Malnutrition in GI tract Cancer patients under surgery
Ricardo Terminel Zaragoza, Parada-Flores OA, Ramos E
and
Rivera-Perez MA
Health Sciences Department,Mexico
Introduction:
Limited resources force hospitals from relying
on nutrition screening tools to identify malnutrition patients.
The Nutritional Control Index (CONUT) increased attention in
the nutritional screening and assessment is due to its simple
and automatized method of three parameters: lymphocytes,
cholesterol and albumin. There is an ongoing debate regarding
the value of albumin as a clinical marker of malnutrition, because
it’saffectedbysystemicinflammation,commoningastrointestinal
cancerpatients.Theobjectiveofthisstudyistoproposeanutritional
screening tool for detecting malnutrition in these patients.
Methods:
This is a randomized, single-blinded, case control
study done in the Mexican Institute for Social Security. An
established number of 50 patients with GI cancer, an output
of <500mL/d and surgery candidates undergo prospective
random assignment to CONUT (n=25, control group) or
IMSS Score (n=25, study group). Weight, cholesterol and
lymphocytes were measured in both groups, with only
difference of albumin for control, and total proteins for study
group, pre and post-surgery (4 days after). Outcome variables
include preoperative and postoperative nutritional status.
Results:
CONUT and IMSS score effectively detected
malnutrition. The pre-operative study group score showed less
cases of moderate malnutrition proved by mean reduction
(mean: 5.2 ± 0.1959) than the control group (mean: 7.52 ±
0.2917) and statistical significance (p<0.0062, r: 0.9629). The
post-operative study group got only moderate malnutrition
cases (mean: 6.8 ±0.1512), while the control group got mixed
several and moderate malnutrition (mean: 9.96± 0.2813),
having the most statistical difference (p<0.0001, r: 0.8886).
Conclusion:
IMSS score was able to significantly provide a
nutritionalstatusinGIcancerpatients,thisstudycouldbeafirststep
for a novel nutritional screening. However, further studies should
be done in more heterogeneous populations and larger sample
s
e:
drritom@gmail.com