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N o v e m b e r 2 1 - 2 2 , 2 0 1 8 | M a d r i d , S p a i n
OF EXCELLENCE
IN INTERNATIONAL
MEETINGS
YEARS
Analytical Chemistry 2018 Journal of Chemical Technology and Applications| Volume 2
ANALYTICAL CHEMISTRY
International Conference on
Kikalishvili B et al., J Chem Tech App 2018, Volume 2
STUDY OF THE LIPIDS FROM THE FRUITS
OF YUGLANS REGIA L. GROWING IN
GEORGIA
Kikalishvili B, Gorgaslidze N, Turabelidze D, Sulakvelidze Ts and
Malania M
TSMU I. Kutateladze Institute of Pharmacochemistry, Georgia
The aim of the investigation is to study on content of lipids fruits of usual
walnut growing in Georgia for the use in medicine, for strengthening med-
ical effect in oncological therapy, also in cosmetology.
Usual walnut - Juglans regia L. (Juglandaceae) is widely spread in Georgia.
The fruit (kernel) of plant is rich in lipids and various classes (groups) physi-
ologically active compounds: vitamins, fatty acids, flavonoids, sterines, ami-
noacids. The fruit of walnut and lipids from them is used for treatment of ath-
erosclerosis, cardio-vascular diseases, in the time of liation immunic system,
dermatitis, depressy, possesses cholagogic action.
From the fruits of walnut there was isolated the sum of neutral lipids (nl)
in ameunt 70%, in which are revealed substances of following classes: hy-
drocarbons, triglycerides, free fettiy acids, sterines. There were determined
some physical-chemical constants of the sum neutral lipids: specific weight
d20 -0,925; index of refraction n20 -1,481; acid number- 1,9mg.KOH; iodine
number I-135.
On the following stage of investigation with the help of method high perfor-
mance liquid chromatography (HPLC) qualitatively and quantitatively there
were identified free fatty acids: dodecanic acid - 0,10 mg/%, tetradecanic
acid - 0,12 mg/%; hexadecanic acid -4,98mg/%; octadecanic acid - 1,4 mg/%;
eicosanic acid - 0,21 mg/%; docosanic acid - 0,15 mg/%; tetracosanic acid
-0,10mg/%; 9-octadecenic acid-70mg%; 9,12-octadecadienic acid-18,6 mg/%
and 9,12,15-octadecatrienic acid-1,8mg%.
In the polar sum of the fruits of walnut there were revealed four phospho-
lipids: lizophosphatidilcholin Rf-0,25; phosphatidilinosit Rf-0,34; phosphati-
dilcholin Rf 0,58; phosphatidilethanolamin Rf 0,64.
The sum of neutral lipids walnut from saturated fatty acids dominates hexa-
decanoic acid, but from unsaturated fatty acids-9-octadetsenic.
By the pharmacologically studies there was established that lipids from the
fruits of walnut possess gastro protectoral action.
Kikalishvili B has completed her PhD at the age of 35
years from I. Kutateladze Institute of Pharmacochemis-
try (Georgia). She is a principal scientist of TSMU Iovel
Kutateladze Institute of Pharmacochemistry. She has
published more than 74 publications in reputed journals.
She is a member of organizing committee of several in-
ternational conferences and meetings.
BIOGRAPHY