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Dermatol Res Skin Care 2017 | Volume 1 Issue 1

World

Dermatologist Summit and Skin Care Expo

October 30-31, 2017 | Toronto, Canada

Facial manifestations of pachydermoperiostosis treated with botulinum toxin type-A (Report of 3 Cases)

Xiang Wen

West China Hospital of Sichuan University, China

achydermoperiostosis (PDP) is an uncommon genetic

syndrome characterized by distinctive digital clubbing,

periostosis and pachydermia. There is no accepted therapy for

alleviating the aesthetic defects associated with pachydermia.

The aim of this study was to evaluate the role and long-term

effect of botulinum toxin type A (BTX-A) in improving facial

manifestations in patients with PDP. Three patients with PDP

were treated with BTX-A. The main outcome measures were

physician rating of wrinkle severity in relaxation, at baseline

and after treatment. Secondary measures were patient

global assessment of improvement. Case one and Case three

were successfully treated with BTX-A; Case two reported an

exacerbation of the eyelid ptosis possibly related to treatment.

Case 1 underwent 4 sets of injections over a 48-week period

which has never been described. We suggest temporal

improvement of cosmetic appearance of patients with PDP

could be achieved by BTX-A injection. Repeated treatments

remained effective.

Speaker Biography

Xiang Wen is an attending Physician in Dermatology Department, West China Hospital

of Sichuan University, China. She has been a Visiting Scholar at Wellman Center for

Photomedicine, Massachusetts General Hospital, Harvard Medical school, USA from

2016 to 2017. She has been engaged in various cosmetic surgeries for several years,

particularly cosmetic lasers and injections. She has over 15 publications and has been

serving as reviewer of reputed Journals.