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Journal of Clinical and Experimental Toxicology | Volume: 2
December 03-04, 2018 | Dubai, UAE
International Conference on
6th International Conference on
Toxicology, Clinical Toxicology & Pharmacology
Recycling & Waste Management
Joint Event
&
Chemical characterization and Toxicity of POEA – 15, surfactant of commercial glyphosate (Round
up) and effect of round up on heavy metals in Paddy Soil
Ayanthi Navaratne
Peradeniya University, Sri Lanka
Use of commercial glyphosate, round up has been a very
controversial issue over the recent past in Sri Lanka due
to the hypothesis that it causes the chronic kidney disease of
unknownetiology(CKDu)prevalentinSriLanka.Consequently,
round up was banned in Sri Lanka in 2015 although it was
re permitted to use in tea and rubber cultivation in 2018.
In this study we report two main findings: First, chemical
characterization and toxicity studies of POEA 15, surfactant
of Round up available in Sri Lanka. Main surfactant of round
up was confirmed to be POEA-15 with an authentic sample.
Toxicity studies conducted with animal experiments (with
rats) and cell lines (Hamster kidney) clearly indicated that
it is a nephrotoxin (at very low concentrations). Second, in
order to study the effect of Round up for the behavior of
heavy metals in rice fields, a detailed study of adsorption
and desorption of heavy metals on paddy soil and the
kinetics of these processes were investigated. According
to the studies performed with paddy soil after application
of Round up, reduced the adsorption and desorption of Cd
(II) on soil in comparison to the other heavy metal cations.
Furthermore, this research also indicated that the soil to
grain (rice) transfer factor was highest for Cd (II). Therefore,
our investigation concluded that POEA -15 is a possible
nephrotoxin and, in the presence of commercial glyphosate,
round up increases the available concentration of Cd (II) in
water phase. Having the highest transfer factor (soil to grain),
there is a possibility of contamination of rice grainwith Cd (II).
Speaker Biography
Ayanthi Navaratne obtained her B. Sc in Chemistry (Honors) from University of Peradeniya
Sri Lanka in 1984 and her MS and PhD in 1989 and 1992 respectively from University of
Hawaii at Manoa, USA in Analytical Chemistry. Currently she is a professor in Chemistry at
the University of Peradeniya and was the Head of the Department of Chemistry from 2005
to 2018. She is a Fellow of National Academy of Science, Sri Lanka (FNASS). She has trained
about 40 postgraduate students and produced many publications in refereed journals
during her carrier.
e
Ayanthi Navaratne, Toxicology 2018 & Recycling 2018, Volume 2
DOI: 10.4066/2630-4570-C1-003