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Journal of Dermatology Research and Skin Care | Volume 2
May 14-15, 2018 | Montreal, Canada
Spring Dermatology &
Skin Care Expo Conference
H
yaluronic acid (HA) is themost-abundant glycosaminoglycan
in the human body and it is made by repetitive sequences
of D-Glucuronic Acid + N-Acetyl D-Glucosamine. Indeed, HA
represents 15% of body weight in individuals weighing around
70Kg; skin represents 50% of total HA in the body; and 1/3 of
total HA in the human body is metabolized daily. HA-based
aesthetic dermal filler has 400-6,000 KDa of molecular weight
and presents a high hygroscopic function for extracellular
matrix (increases immediately in 15% its volume). Based on
the short 12-hour half-life of a noncross linked HA-based
filler, scientists created cross linked HA-based fillers that have
better stability against metalloproteinase and a long-lasting
durability. However, such manufacture profile impacts directly
on the HA-based product rheological properties (rheology is
the study of the flow of matter of a product, under external
conditions in which they respond with plastic flow rather
than deforming elastically in response to an applied force). In
this lecture, the speaker will explore the different rheological
properties of different commercial HA-based fillers, based on
they manufacture process.
Speaker Biography
Adilson Da Costa is a Brazilian dermatologist that lives in Atlanta, GA, USA. He got
his MD from Santa Casa of Sao Paulo School of Medicine, wherein he also completed
his specialization in Dermatology. He obtained his MSc in Dermatology from Federal
University of Sao Paulo, PhD from the University of Sao Paulo School of Medicine and
he did his Postdoctoral Research Fellowship in Dermatology at Emory University School
of Medicine, Atlanta, GA, USA. Currently, he is a Tenured Professor for the PhD and MSc
Programs at the State of Sao Paulo Workers’ Welfare Institute, Sao Paulo, SP, Brazil.
He is a very experienced Researcher in Dermatology and has served as a Principal
Investigator in more than 150 projects, either clinical or
in vitro
, which helped him to
take place as an Advisory Board Member for important companies, such as Galderma,
Sinclair, Avon, L’Oréal, Hypermarcas, and Natura; moreover, his research skills has
helped him to be a common scientific resource for the general media, and an frequent
speaker in international scientific meetings. He has already two books published
“Dermatology in Pregnancy” (Guanabara Koogan) and International Textbook of
Cosmeceuticals
(Elsevier) and is now working on an international masterpiece on
dermatological procedures. He has more than 60 manuscripts and chapter of books
already published.
e:
adilson_costa@hotmail.comAdilson Da Costa
Orange County Plastic Surgery, USA
Rheological aspect of hyaluronic acid fillers