spring-dermatology-skin-care-2018-tracks

8 / 35

Page 23
Notes:
alliedacademies
Journal of Dermatology Research and Skin Care | Volume 2
May 14-15, 2018 | Montreal, Canada
Spring Dermatology &
Skin Care Expo Conference
Botulinum toxin type A (BoNT-A) has been used for many
dermatological conditions, apart from aesthetic treatments
and focal hyperhidrosis. In keloids and hypertrofic scars,
botulinumtoxinmayalleviate tensiononwoundedges, resulting
in superior cosmetic outcome. Lower sebum production and
decreased pores size were observed after intradermal BoNT-A
facial applications. BoNT –A inhibits nerve-derived release of
calcitonin gene-related peptide and substance P, resulting in
psoriasis remission. In androgenetic alopecia, BoNT-A reduces
pressure on vasculature and increases blood flow, which results
in the reduction of the enzymatic conversion of testosterone
to dihydrotestosterone. Patients with Raynaud phenomenon
experienced resolution of pain and healing of digital ulcers. The
reduction on sweat production can diminish skin flora and its
proinflammatory effect in cases of hidradenitis suppurativa and
Hailey-HaileyDisease. Improvement of pruritus and vesiculation
confirmed efficacy of BoNT-A in dyshidrotic eczema. The
injection of botulin toxin may reduce various substances
that sensitize nociceptors, thus having an analgesic role on
neuropatic pain, such as postherpetic neuralgia. Improvement
in pruritus was also seen in notalgia paresthetica.
Speaker Biography
Renata Indelicato Zac is a Brazilian Dermatologist and has her expertise in clinical and
cosmetic dermatology and is pursuing her Master’s degree in Health Science. She is
the Director of Clinica Attento, Belo Horizonte, MG, Brazil, and Mentor in dermatology
training at Minas Gerais’ Military Hospital.
e:
Renata Indelicato Zac
Minas Gerais’ Military Hospital, Brazil
Non-conventional use of botulinum toxin in cosmetic dermatology