2 / 17
allied
academies
Page 33
April 15-16, 2019 | Frankfurt, Germany
Applied Physics & Laser, Optics and Photonics
International Conference on
Materials Science and Nanotechnology | Volume: 3
Study of electromagnetic spectrum of nano-sized viral particles via simulation
Tamar Bzhalava
1
, Mzia Tsirekidze
1
and
Levan Goderdzishvili
2
1
Georgian Technical University, Georgia
2
Free University, Georgia
S
tudy of spectral characteristics of nano-sized
viral particles, virions the extracellular infective
forms of viruses is proposed. Morphology of virions
is icosahedral, prolate or helical, size of that varies
from 20 to 300 nm. Based on structure analysis of
virions, consisting of inner core of nucleic-acids
(RNA or DNA) and outer protective protein coat
(capsid), the core-shell model of virus-like particle
(VLP) is considered for simulation.
The single-particle study of electromagnetic (EM)
wave & VLP interaction is based on Maxwell
EM theory, separation of variables method for
solving Helmholtz equation. Theoretical solution
of electrodynamics boundary problem is applied
for determination of EM fields in the areas of
core, shell and surrounding medium of nano-sized
particles. EM fields are presented as the sum of
multipole wave-modes, number of that depends
on “electrical” size of particles and is defined
empirically within prescribed accuracy. Expected
spectral “response” is observable on far-field
characterizations and strongly depends on core-
shell related electric and geometric parameters of
VLP, especially in resonance wavelength range.
Computer simulation (based on MatLabR2013b)
is used for studying EM field characteristics vs
excitation wave length, for appreciation of possible
resonant wave range correlating with scattering
efficiency of VLP. VLP “spectrum” is demonstrated
for cylindrical nanoparticle, namely un-enveloped
rod-like virion of Tobacco Mosaic Virus (TMV),
deciding 2D boundary problem.
Proposed methodology for modelling of EM spectra
of virions seems to be a simpler way in determining
the spectral response of whole viral particle, which
in complement with experimental spectroscopic
studies could solve the problem of defining the
unique and specific “fingerprints” important in nano-
bio-particles characterization. Findings are applicable
in nano-bioparticles detection and identification
systems, aerosol spectroscopic studies as well.
The work was carrying out in GTU supported by
ShotaRustaveli National Science Foundation (SRNSF)
under Grant Agreement (FR/430/3-250/13).
Speaker Biography
Tamar Bzhalava is an associate professor at the Department of Engineering
Physics, Georgian Technical University (GTU). She was the candidate
(PhD) of Physics and Mathematics Sciences (1990). She was the scientific
manager (2014-2017) of grant project of Shota Rustaveli National
Science Foundation (SRNSF) - “Nano-Sensory Applications for Studying-
Elaboration of Detecting Model of Pathogenic Microorganisms”. She is
the member of scientific team elaborated successful international and
local Scientific Projects: SENS-ERA, FP7-INCO-2011-6 (2013); International
Science and Technology Centre (ISTC) grants (2006-2009, 2003-2004);
Georgia National Science Foundation (GNSF) grant (2006-2008). She has
been a participant and member of organizing committees of international
and national scientific conferences, workshops. She is an author up to 70
scientific publications, text books, Principle of Master Program at GTU.
Her research interests mainly focus on oscillation, scattering, spectral
properties of nano-micro-particles, EM-wave & particles interaction,
applied electrodynamics, teaching general physics, modeling, simulation.
e:
tamar.bzhalava@gtu.ge