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O c t o b e r 1 5 - 1 6 , 2 0 1 8 | T o k y o , J a p a n

Obesity Congress 2018, Diabetes Congress 2018 & Vaccines Congress 2018

Biomedical Research

ISSN: 0976-1683

Volume 29

WORLD OBESITY CONGRESS

WORLD VACCINES AND IMMUNOLOGY CONGRESS

DIABETES AND ENDOCRINOLOGY

International Conference on

Joint Event on

OF EXCELLENCE

IN INTERNATIONAL

MEETINGS

YEARS

Biomed Res 2018, Volume 29 | DOI: 10.4066/biomedicalresearch-C5-014

TRIMESTER-SPECIFIC REFERENCE INTERVALS OF THYROID FUNCTION

TESTING IN PREGNANT WOMEN FROM BASRAH, IRAQ USING ELECTRO-

CHEMILUMINESCENT IMMUNOASSAY

Ammar Mohammed Saeed Almomin

, Abbas Ali Mansour

and

Maysoon Sharief

Al-Faiha Specialized Diabetes, Endocrine and Metabolism Center, Iraq

Basrah College of Medicine, Iraq

Background:

Thyroid function test results of healthy pregnant women differ from those of healthy non-pregnant women. This

study aimed to determine trimester-specific reference ranges for total tetraiodothyronine (T4), free T4, total triiodothyronin (T3)

and thyroid stimulation hormone (TSH) using electrochemiluminescence techniques from apparently healthy pregnant women

in Basrah.

Material & Methods:

A cross sectional study was conducted between January 2014 and June 2015. The total enrolled pregnant

women were 893. Clinical examination, estimation of free T4, total T4, total T3, TSH and anti-thyroid peroxidase (anti-TPO) using

electrochemiluminescence technique done for each.

Results:

Trimester specific normal range of TSH in _IU/mL was 0.04–3.77, 0.30–3.21 and 0.60–4.50 _IU/mL respectively, for

each trimester. For FreeT4, the trimester specific reference range was 0.8–1.53, 0.7–1.20 and 0.7–1.20 ng/dL for each trimester,

respectively. The reference range for total T4 for the first, second and third trimester was 7.31–15.00, 8.92–17.38 and 7.98–17.70

_g/dL, respectively. Furthermore, last trimester specific reference range for total T3 was 0.90–2.51, 1.99–2.87 and 1.20–2.70 ng/

mL, respectively.

Conclusion:

Using this thyroid function study, we established for first time trimester-specific reference ranges for each thyroid

function test and thyroid antibody status for the first time in Iraq. The reference ranges are different from all previous studies

outside Iraq and the reference kit range from the method we used.