obesity-congress-diabetes-congress-2018-posters

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O c t o b e r 1 5 - 1 6 , 2 0 1 8 | T o k y o , J a p a n

Obesity Congress 2018, Diabetes Congress 2018 & Vaccines Congress 2018

Biomedical Research

ISSN: 0976-1683

Volume 29

WORLD OBESITY CONGRESS

WORLD VACCINES AND IMMUNOLOGY CONGRESS

DIABETES AND ENDOCRINOLOGY

International Conference on

Joint Event on

OF EXCELLENCE

IN INTERNATIONAL

MEETINGS

YEARS

Biomed Res 2018, Volume 29 | DOI: 10.4066/biomedicalresearch-C5-014

COMPARISON OF RISK FACTORS AND PREGNANCY OUTCOMES OF

GESTATIONAL DIABETES MELLITUS DIAGNOSED DURING EARLY AND

LATE PREGNANCY

Mohsen Janghorbani

and

Elham Hosseini

Isfahan University of Medical Sciences, Iran

Objectives:

To compare risk factors and pregnancy outcomes of gestational diabetes mellitus (GDM) diagnosed during early

and late pregnancy.

Methods:

929 diabetes-free pregnant women who were eligible and consented to take part underwent fasting plasma glucose

testing at the first prenatal visit. The women free from GDM or overt diabetes were screened at 24-28 weeks of gestation using

a 75-g, 2-hour oral glucose tolerance test. The diagnosis of GDM was reached through the International Association of the Dia-

betes and Pregnancy Study Groups. Early-onset GDMwas defined as the diagnosis of GDM at the first prenatal visit (6-14 weeks

of gestation). Late-onset GDM was defined as the diagnosis of GDM later at 24-28 weeks.

Results:

Prevalence of GDM was 10% (95% CI: 8.1-11.9) at the first prenatal visit. GDM incidence was 9.3% (95% CI: 7.4-11.2) at

24-28 weeks. Family history of diabetes, and previous gestational diabetes and maternal age were the independent risk factors

for GDM during early and late diagnosis. GDM was associated with increased risk of macrosomia, large for gestational age, and

cesarean section in both periods while, neonates of women with early-onset GDM were more likely to have an Apgar score at

1-minute <7, and neonatal respiratory distress syndrome and were more admitted to the neonatal intensive care unit.

Conclusion:

Early-onset GDM was associated with poorer pregnancy outcomes indicating the need for further research to in-

vestigate the alternative management approaches that could improve diabetes-related complications and outcomes in these

women.