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academies
Nov 12-13, 2018 | Paris, France
Nutraceuticals and Food Sciences
International Conference on
27
th
International Conference on
Nursing and Healthcare
&
Joint Event
Journal of Food science and Nutrition | Volume 1
The use of Oral Probiotics in the prevention of upper respiratory tract infections
Alessandro Bucci
Hospital of Senigallia, Italy
A
t the start of the 20th century (in 1908), Russian noble prize
winner and father of modern immunology, E. Metchnikoff,
a scientist at the Pasteur institute, observed that a surprising
number of people in Bulgaria lived more than 100 years.
Metchnikoff observed that Bulgarian peasants consumed large
quantities of “yogurt”. He subsequently isolated bacteria from
the yogurt and determined that they conferred the observed
health-promoting benefits. The clinical evidence for application
of the interfering ability of non-virulent bacteria to prevent or
treat infections has been rather limited, although promising
for certain purposes. Bacterial interference refers to the
antagonism between bacterial species during the process of
surfacecolonisationandacquisitionofnutrients.Conventionally,
probiotics, defined by the WHO as ‘live organisms which, when
administered in adequate amounts confer a health benefit on
the host’, have almost exclusively been bacteria of intestinal
origin, and their application has largely been targeted at
relieving maladies of the gastrointestinal tract. A number of
relevant preliminary trials suggest that in the upper respiratory
tract the rate of recurrence of streptococcal pharyngotonsillitis
appears to decrease using selected bacteria with inhibitory
ability against common pathogens of upper respiratory tract.
Sore throat is one of the most common reasons for visits to
family physicians or paediatrician. URTIs are very common and
cause substantial illness and billions of dollars of economic
loss every year. Streptococcus pyogenes is a major cause
of acute pharyngeal infections, especially in children. Oral
probiotic as Streptococcus salivarius K12 has been shown
clearly to antagonize the growth of Streptococcus pyogenes,
the most important bacterial cause of pharyngeal infections
in humans, by releasing two bacteriocins named salivaricin
A2 and salivaricin B, reducing the incidence of streptococcal
pharyngitis and/or tonsillitis. According to our reviews of the
literature and our experience prophylactic administration of
Streptococcus salivarius K12 to adults and/or children having
a history of recurrent oral streptococcal pathology reduces the
number of episodes of streptococcal pharyngeal infections and/
or tonsillitis.
Speaker Biography
Alesaandro Bucci is the Centre and Rhinology/Rhino-Allergology Centre - Otolaryngology
Dept. ASUR Marche – AV2 – Senigallia – Italy. International faculty member of the XXXV
Pan-American Congress of Otorhinolaryngology 2016, Cuba. Past Director of the 1st
International Conference on Rhinology and Rhino-Allergology / 5th Bulgarian Italian
Rhinology Meeting, 2016 Senigallia (Italy). Committee Member and Chairman of the
International Specialists Conference on Ear, Nose and Throat Disorders, November
2016 Alicante (Spain). In the past: University Professor at the UNIVPM – Ancona –
Italy. International faculty member of the VI Bulgarian Italian Meeting of Rhinology. Dr.
Bucci attended medical school at Catholic University (UCSC) in Rome, and completed
his residency in Otolaryngology-Head and Neck Surgery at UCSC - Gemelli Hospital in
Rome. Reserve Medical Officer of the Italian Navy. Consultant in Otolaryngology from
2002. PhD (Rhinology and Rhino-Allergology) in 2006 at UCSC - Rome. Fellowship in
Otolaryngology in Spain (University Hospital, Cadiz). Fellowship trained in Facial Plastic
Surgery (AMC) and OSAS (Sint Lucas Andreas Hospital) in Amsterdam, The Netherlands,
in Facial Plastic Surgery (Calixto Garcia University Hospital), La Habana, Cuba. Research
focused on Rhinology/RhinoAllergology, Sleep Apnea/OSAS, and dysphagia/swallowing
disorders. Teaching, management and audit experienced. His other main interest
is in humanitarian and international outreach. He is Vice-president of the ONLUS
association:
“ANATRA.it”(National Association of Tracheotomised patients). Member of
the ERS (European Rhinologic Society). Hobbies are sailing / windsurfing, world music,
travel and diving (PADI).
e:
drbucci@libero.it