neuroscience-2018-posters-abstracts

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Volume 2

June 11-13, 2018 | London, UK

Neurology and Neuroscience

International Conference on

Benefit effects of roller technique in inflammation induced by notexin

Joaquín Barrachina-Igual, Ana Pablos, Pilar Rivera

and

Soraya L. Valles

University of Valencia, Spain

oller technique has been involved in the recovery of

neuronal, vascular and muscles damage. Using rats

(7 months age) treated with Notexin and Notexin + roller

technique, we determined changes in inflammation proteins

and cell death by Western-blot. An increase in NFκB and

a decrease in PPAR-γ protein expression were noted after

Notexine addition. Treatment with Notexin + roller technique

produced a decrease in NFκB pro-inflamatory protein with an

increase in PPAR-γ anti-inflammatory protein compared to

Notexin samples. Looking by changes in vascular new genesis

after muscle damage, we detect decrease in VEGF and VEGFR1

protein expression produced after Notexin action. On the other

hand, an increase of both proteins in Notexin + roller samples

was observed compared to Notexine. To determine changes

in apoptosis, we assay Smack/Diablo, AIF and Cytochrome c

protein expressions. Roller technique, diminished apoptosis

produced by Notexin addition in all apoptosis proteins. In

conclusion, roller technique produced recovery from damage

induced by Notexin, reducing inflammation and cell death. The

introductionof this technique in athleteswill benecessary in the

future to obtain early and better recovery after tissue damage.

Speaker Biography

Joaquín Barrachina-Igual was born in 22 of October 1996. He has a degree in

Physical Activity and Sport Science, by Catholic University of Valencia (2010-

2014). His Master’s Degree was in “Teacher Training Secondary, Baccalaureate,

Vocational Training and Language Teaching” (2015). At this moment he is doing

his PhD with a Doctoral Fellowship with Reference number ACIF72017/126 from

“Generalitat of Valencia”, Spain, (from 2016 until 2020) and with the title, “Effect

of High Intensity Strength Training and Myofascial Self-Conditioning on Sacopenia

in Frail Elderly and Pre-frail Elderly” Catholic University of Valencia, best University

record of the 2014 promotion Languages English, level B2 (First Certificate) (2015).