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Mater Sci Nanotechnol 2017 | Volume 1 Issue 2
allied
academies
Nanomaterials and Nanochemistry
November 29-30, 2017 | Atlanta, USA
International Conference on
I
n recent years, DNA has been used as an ideal substrate
for the engineering of versatile nanostructures and
nanomachines due to its well characterized conformation
and predictable self-assembly. Using non-overlapping sticky-
end cohesion, DNA nanostructures can be modified in a
number of ways for the site-directed spatial arrangement
of functional guest components such as proteins, metal
nanoparticles, and small molecules with high accuracy. This
talk will review the state of DNA nanotechnology including
DNA-based sensors, DNA-actuated enzyme nanoreactors,
fluorescence-force measurements of motor proteins on DNA
origami platforms, and other emerging biotechnological
applications of one-, two- and three-dimensional DNA
nanostructures.
Speaker Biography
Soma Dhakal has completed his Ph.D from Kent State University, USA in 2013. After
three years of postdoctoral research at the University of Michigan, he joined Virginia
Common Wealth University (VCU), USA as an Assistant Professor in the Department of
Chemistry where he started his state-of-the art DNA nanotechnology lab. His research
is highly interdisciplinary which spans from DNA nanotechnology to single-molecule
DNA/protein biophysics and aptamer-based single-molecule sensing. The main
research theme of his group is to exploit the programmability of DNA nanostructures
for both material as well as biological applications. He is co-author of a book chapter
and several publications in high-impact scientific journals. His work has been featured
in news outlets such as Nature News and Views, C&EN News, and
Phys.Org.He has
served as a peer reviewer for several reputed journals and funding agencies.
e:
sndhakal@vcu.eduSoma Dhakal
Virginia Commonwealth University, USA
From material to biotechnology applications of structural DNA nanotechnology