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Mater Sci Nanotechnol 2017 | Volume 1 Issue 2

allied

academies

Nanomaterials and Nanochemistry

November 29-30, 2017 | Atlanta, USA

International Conference on

I

n recent years, DNA has been used as an ideal substrate

for the engineering of versatile nanostructures and

nanomachines due to its well characterized conformation

and predictable self-assembly. Using non-overlapping sticky-

end cohesion, DNA nanostructures can be modified in a

number of ways for the site-directed spatial arrangement

of functional guest components such as proteins, metal

nanoparticles, and small molecules with high accuracy. This

talk will review the state of DNA nanotechnology including

DNA-based sensors, DNA-actuated enzyme nanoreactors,

fluorescence-force measurements of motor proteins on DNA

origami platforms, and other emerging biotechnological

applications of one-, two- and three-dimensional DNA

nanostructures.

Speaker Biography

Soma Dhakal has completed his Ph.D from Kent State University, USA in 2013. After

three years of postdoctoral research at the University of Michigan, he joined Virginia

Common Wealth University (VCU), USA as an Assistant Professor in the Department of

Chemistry where he started his state-of-the art DNA nanotechnology lab. His research

is highly interdisciplinary which spans from DNA nanotechnology to single-molecule

DNA/protein biophysics and aptamer-based single-molecule sensing. The main

research theme of his group is to exploit the programmability of DNA nanostructures

for both material as well as biological applications. He is co-author of a book chapter

and several publications in high-impact scientific journals. His work has been featured

in news outlets such as Nature News and Views, C&EN News, and

Phys.Org.

He has

served as a peer reviewer for several reputed journals and funding agencies.

e:

sndhakal@vcu.edu

Soma Dhakal

Virginia Commonwealth University, USA

From material to biotechnology applications of structural DNA nanotechnology