materials-summit-separation-summit-2018-posters

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O c t o b e r 1 9 - 2 0 , 2 0 1 8 | T o k y o , J a p a n

Materials Summit 2018 & Separation Summit 2018

Materials Science and Nanotechnology

Volume 2

ADVANCED MATERIALS AND POLYMER SCIENCE

SEPARATION TECHNIQUES

International Conference on

International Conference and Expo on

Joint Event on

OF EXCELLENCE

IN INTERNATIONAL

MEETINGS

YEARS

Mater Sci Nanotechnol 2018, Volume 2

USE OF NONOPERATION FOR CURE OF TUMOR AS A SEPARATION

TECHNIQUE

Diksha Singh

King George Medical College, India

ltrasound is an emerging modality for drug delivery in chemotherapy. This poster reviews this novel technology by first intro-

ducing the designs and characteristics of three classes of drug/gene vehicles, microbubble (including nanoemulsion), lipo-

somes, and micelles. In comparison to conventional free drug, the targeted drug-release and delivery through vessel wall and in-

terstitial space to cancerous cells can be activated and enhanced under certain sonication conditions. In the acoustic field, there

are several reactions of these drug vehicles, including hyperthermia, bubble cavitation, sonoporation and sonodynamics, whose

physical properties are illustrated for better understanding of this approach.

In vitro

and

in vivo

results are summarized, and fu-

ture directions are discussed. Altogether, ultrasound-mediated drug/gene delivery under imaging guidance provides a promising

option in cancer treatment with enhanced agent release and site specificity and reduced toxicity. This review poster presents the

methodology to treat invasive cancer in a non-invasive manner, by successfully penetrating through the biological membranes.