materials-summit-separation-summit-2018-posters

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O c t o b e r 1 9 - 2 0 , 2 0 1 8 | T o k y o , J a p a n

Materials Summit 2018 & Separation Summit 2018

Materials Science and Nanotechnology

Volume 2

ADVANCED MATERIALS AND POLYMER SCIENCE

SEPARATION TECHNIQUES

International Conference on

International Conference and Expo on

Joint Event on

OF EXCELLENCE

IN INTERNATIONAL

MEETINGS

YEARS

Mater Sci Nanotechnol 2018, Volume 2

RADIOIODINATION, CHROMATOGRAPHIC SEPARATION AND BIOLOGICAL

EVALUATION OF CIMENTIDINE AS A NEW HIGHLY SELECTIVE

RADIOTRACER FOR PEPTIC ULCER DISORDER DETECTION

M H Sanad

, H M Eyssa

and

H T Salem

Labeled Compounds Department, Radioisotopes Production and Radioactive Sources Division, Egypt

Radiation Chemistry Dept., National Centre for Radiation Research and Technology (NCRRT), Egypt

Health Radiation Research department (Radiodiagnosis Unit), National Center for Radiation Research and Technology, Egypt

imentidine has been labeled using [125I] with chloramine-T (Ch-T) or N-Bromosuccinimide (NBS) as different oxidizing agents.

Factors such as amount of substrate, reaction temperature, pH, reaction time and, different oxidizing agents have been

systematically studied to optimize the iodination. The radiochemical conversion was calculated on thin-layer chromatography

(TLC), paper electrophoresis (PC), gel filtration (GF), and then completely purified by high performance liquid chromatography

(HPLC). An optimum conversion of 98% was achieved. Biodistribution studies indicate the suitability of [125I]iodocimetidine

as a novel tracer to image stomach ulcer. current trends, innovations and methodology in 3D printing. It came up with a theme

“Innovations in Medicine through 3D Printing”.