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Journal of Materials Science and Nanotechnology | Volume 2
July 23-25, 2018 | Moscow, Russia
Materials Science and Engineering
International Conference on
Calcium phosphate-based Biomaterials
Sergey V Dorozhkin
Moscow Institute of Chemical Technology, Russia
C
alcium phosphates (CaPO
4
) are of the special significance
for the human beings because they represent the inorganic
part ofmajor normal (bones, teethandantlers) andpathological
(those appearing due to various diseases) calcified tissues of
mammals. For example, atherosclerosis results in blood vessel
blockage caused by a solid composite of cholesterol with
CaPO
4
, while dental caries (tooth decay) and osteoporosis (a
low bone mass with microarchitectural changes) mean a partial
decalcification of teeth and bones, respectively, that results in
replacement of a less soluble and harder biological apatite by
more soluble and softer calcium hydrogen orthophosphates.
Althoughthebiologicalmechanismsappeartobequitedifferent,
chemically, the processes of both normal and pathological
calcifications might be considered as an in vivo crystallization
of CaPO4. Similarly, dental caries and osteoporosis might be
considered as an in vivo dissolution of biologically formed
CaPO
4
. Due to the compositional similarities to the calcified
tissues of mammals, CaPO
4
are widely used as biomaterials for
bone grafting purposes. In addition, CaPO
4
have many other
applications. Namely, natural CaPO
4
are the major source of
phosphorus, which is used to produce agricultural fertilizers,
detergents and various phosphorus-containing chemicals.
Speaker Biography
Sergey V Dorozhkin received his MSc in chemical engineering with honors in 1984 from
Moscow Institute of Chemical Technology, Moscow, Russia, and his PhD in chemistry in
1992 from the Research Institute of Fertilizers, Moscow, Russia. From 1992 to 1994 he
worked as a senior researcher at the same institute, and from 1994 to 1996 he worked
as a biotechnologist at a Swiss-Russia joint venture. From 1996 to 2004 he held five
postdoctoral positions in France, Portugal, Germany and Canada where he worked on
various aspects of calcium phosphates. He has authored more than eighty research
papers, about thirty reviews, twenty-five book chapters and seven monographs. All
these publications have been cited over 5000 times and his publication H-index is 30.
e:
sedorozhkin@yandex.ru