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Curr Trend Cardiol. 2017 | Volume 1 Issue 3

September 18-19, 2017 | Toronto, Canada

Annual Conference on

HEART DISEASES

Background:

Coronary artery disease is a major cause of

morbidity and mortality across the globe. Although rich

data is available regarding clinical profile of acute coronary

syndrome (ACS) patients in the western world, very few

studies have been done in Punjab population in India. Our

study will contribute towards filling this gap.

Aim:

To study clinical profile, risk factors, angiographic

findings and immediate and short term mortality statistics in

ACS patients of Punjab, India.

Materials and Methods:

It was a prospective observational

study done on the ACS patients who were admitted to Guru

Nanak Dev Hospital/ Government Medical College Amritsar

between the period from July 2016 to June 2017.

Results:

In this study 393 patients with ACS were recruited.

Out of these 299 (79.08%) were males and 94 (23.92%) were

females. The mean age of our population was 64.52 ± 11.04.

Hypertension was present as a risk factor in 301 patients

(76.59%), 263 patients (66.92%) were smokers, 234 (61.83%)

had BMI more than 25, while 35 patients (4.33%) had a family

member with was diagnosed with ACS. 55 patients (31.99%)

were classified in advanced Killip class (Class 3 or 4) at the

time of presentation. 263 patients (66.92%) had ST segment

elevation myocardial infaction (STEMI), 113 (28.75%) had

non- ST segment elevation myocardial infaction (NSTEMI),

while 17 (4.33%) patients were diagnosed to have unstable

angina(UA). Most patients had involvement of single vessel

disease (N=230, 58.52%). 73 patients (18.58%) patients had

double vessel disease, 44 patients (11.20%) patients had

triple vessel disease, while 7 patients (1.78%) had left main

vessel involvement. Diabetic patients had more chances of

mortality as compared to non diabetics during initial hospital

admission (N= 21, 12.73% Vs N=13, 5.70%, p value <0.05) as

well as during 30 day follow up period (N= 11, 7.64% Vs N=7.

3.26%, p value <0.05).

Conclusion:

LAD was most commonly involved vessel,

followed by LCX and RCA respectively, Hypertension and

smoking were two most commonly associated risk factors

with ACS. Diabetes in ACS patients leads to more aggressive

course of disease and leads to higher mortality as compared

to non-diabetic ACS patients.

Speaker Biography

Nirankar Singh Neki, MBBS, MD(Internal Medicine) is working as Professor and Head of

Medicine unit 2 at Govt. Medical College Amritsar, India. He has teaching experience

of 30 years as undergraduate teacher and 28 years as postgraduate teacher. He has an

entry in the Limca Book of Records of 2015 for being the recipient of four Fellowships

of the Royal College of Physicians (Edinbourgh, Glasgow, Ireland and London). In total

he has 38 fellowship awards with different institutes. He is receipient of FACC(USA),

FAHA(USA), FESC, FACP(USA),and holds name in cardiology .Dr. Neki holds 13 different

Oration Awards and has been a named author in 365 scientific publications, including

book chapters. He is also Editor in Chief, Senior Editor, Editor, Section Editor, and

Associate Editor of more than 13 national and international medical journals. Dr. Neki

has been a Visiting Professor at James Cook University Hospital in Durham, UK and

at the University of Manitoba’s Institute of Cardiovascular Sciences at St. Boniface

Hospital &Research Centre, Winnipeg, Canada.

e:

drneki123@gmail.com

Clinical profile of acute coronary syndrome in tertiary care hospital of northern India, Punjab

Nirankar Singh Neki

and

Jaswinder Singh

Government Medical College, India