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Journal of Public Health Policy and Planning | Volume 3

April 08-09, 2019 | Zurich, Switzerland

Health Care and Neuroscience

International Conference on

Investigation of the levels of blood MDA, GSH and NO in Alzheimer

Aysel Güven,

Kezban Yildiz Dalginli,

Hacer Çulhaoğlu,

Nergis Hüseyinoğlu

and

Selen İlan Alp

Başkent University, Turkey

Kafkas University, Turkey

he focus of this dissertation is the research

of MDA, GSH and NO levels in the blood of

Alzheimer patients. 15 healthy individuals and

15 Alzheimer patients living in Kars between

the ages 65 to 79 were selected for the

dissertation. Before taking blood samples from

patients who were diagnosed with Alzheimer at

Kafkas University Medicine School Neurology

Center, they were applied Standardized Mini

Mental State Examination (SMMSE) and Clinical

Dementia Rating (Berg L 1984). In the next

step, erythrocyte GSH and plasma MDA, NO

levels were checked. The statistical difference

between the healthy individual and Alzheimer

patient Group erythrocyte GSH (p< 0.01) and

plasma MDA (p< 0.01), NO ( P< 0.01 ) levels

were plausible. As a result, it was observed that

Alzheimer disease caused lipid peroxidation and

as a conclusion significantly increased the MDA,

GSH and NO levels in the blood of Alzheimer

patients. AH'da part of the study, NO level of

the brain related to learning and memory can be

increased by the nNOS and iNOS was concluded.

Speaker Biography

Aysel Güven is a lecturer at Başkent Üniversitesi working in Pathology

Laboratory Bağlıca Campus. She received her PhD in 2000 from Kafkas

University, Turkey and masters from Firat University in the year 1993.