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allied
academies
August 27-28, 2018 | London, UK
International Conference on
Healthcare and Health Management
Cardiology and Cardiac Surgery
Joint Event
&
Journal of Public Health Policy and Planning | Volume: 2
Expandable polyurethane stent valve, as an option for pediatric patients with valve diseases: Result of
physical, hydrodynamic and experimental studies
Miguel Maluf
São Paulo Federal University, Brazil
Background:
A Expandable Polyurethane Stent Valve®,
(EPSV), with a special design for pediatric patients, may be
an option for biological prostheses, whose calcification or
mismatch, in child’s development, shorten their durability.
Methods:
An expandable chrome - cobalt stent, was applied
polyurethane, for the formation of three cuspids, without
sewing, it was sumitted to:1- In vitro tests: I- Physical test.
Universal tests of samples of PU crimped and non-crimped
was performed: A- Strength versus deformation (stretching).
B- Scanner for surface for mechanical properties. II-
Hydrodynamic test. Using a pulsatile flow, to register: valvular
area, pressure gradient and valve regurgitation. 2- In vivo test:
III- Experimental: Ten sheep were submitted to implantation of
expandable polyurethane stent valve by catheter, in pulmonary
position, using right ventricle approach. Expansion diameter:
Group A: 22mm (7 cases) and Group B: 18mm (3 cases).
Results:
I - In vitro tests: PU showed to be a thermoplastic
structure with high deformation, resistant to crimping and
elongation. The hydrodynamic test showed low gradients
and absent or trivial regurgitation of the prosthesis. 2- In vivo
tests: After 5th months of follow-up, a 3D echocardiographic
study, was performed in eight survival sheep and showed:
satisfactory hemodynamic performance, with no significant
transvalvular gradient (M = 6.60 mmHg), absent or trivial
valvular regurgitation, absent leak and free of calcification. Five
survival implanted sheep are well after 24 months of follow up
Conclusions:
Monitoring of favorable results, confirms
that the expandable PU stent valve, can be implanted in
pulmonar position in growing children, below 7 years, during
conventional surgery and above 7 years, by peripheral vessels.
e
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