diabetes-congress-nutrition-2018-keynote

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allied

academies

Nov 22-23, 2018 | Paris, France

Joint Event

Nutrition and Health

International Conference on

Diabetes and Endocrinology

Journal of Insights in Nutrition and Metabolism | Volume 2

Notes:

atural products, especially plant extracts, have beenused

for thousands of years for maintaining health vigor and

for prevention and treatment of diseases. With the current

world population at seven and-half billion, rising health care

costs, and drug resistance, the use of complementary and

alternative medicine is inevitable. Out of the US and Europe,

80% of people rely on dietary supplements. Presently, 150

million Americans consume at least one supplement every

day. These complementary and alternative medicines are

also referred to as Ayurvedic, Unani, traditional Chinese

medicines, etc. In 1989, Dr. Stephen De Felice coined the

term “Nutraceutical” from “Nutrition” and “Pharmaceutical”

and defined it as “A food (or part of a food) that provides

medical or health benefits, including the prevention and/

or treatment of a disease”. By the turn of the 21st century,

the use of nutraceuticals has exploded to safeguard human

and animal health. Currently, revenue of the nutraceutical

industry is more than $250 billion per year. From a “One

Health” perspective, nutraceuticals are used for infectious

and non-infectious diseases in humans and animals. By

having antioxidative, anti-inflammatory, immunomodulatory,

cytoprotective, antimicrobial, anti-parasitic, anti-fungal and

many other properties, nutraceuticals are used for cardiac,

respiratory, hepatic, neurodegenerative (Alzheimer’s and

Parkinson’s), diabetes, arthritis, cancer, and other ailments.

Additionally, phytochemicals are playing a vital role in

controlling vectors and thereby mitigating the spread of

diseases such as malaria, West Nile, dengue, and others

around the globe. In spite of their worldwide use in human

and animal health, nutraceuticals lack mechanistic rationale

and quality standards compared to pharmacotherapeutic

drugs because of their inadequate efficacy, safety and

toxicity evaluation, lack of clinical studies, and inadequate

regulatory guidelines. In the US, the only major regulation

related to nutraceuticals is the 1994 passage of the Dietary

Supplement Health and Education Act by the US Congress. If

Farm Bill 2018 is passed by the US Congress, then cannabis,

for pain management, atopic dermatitis, osteoarthritis, and

many other health conditions, will be the most popular

nutraceutical. In the EU, current regulations require evidence

that herbal medicinal products meet acceptable standards of

quality, safety, and efficacy before a product can be issued.

Currently, the nutraceutical industry is facing too many

challenges, including quality control, evidence of therapeutic

efficacy, food-nutraceutical-pharmaceutical interaction, and

assurance of product safety. By all means, the future of

nutraceuticals in human and animal health seems bright as

novel nutraceuticals will divulge optimal efficacy with few or

no side effects.

Speaker Biography

Ramesh C Gupta, earned his DVM, MVSc, and PhD in India, and carried out his postdoctoral

training at Michigan State University (1981-1983) and Vanderbilt University (1983-1987) in

the US. Currently, he serves as professor and head of the Toxicology Department, Murray

State University. For more than 35 years, he has conducted experimental brain research

in relation to pesticide and neurodegenerative diseases, and for the last twenty years

has been heavily engaged in nutraceuticals research. He has made presentations in the

UK, France, Australia, Italy, Japan, Germany, Switzerland, Spain, Czech Republic, Sweden,

Finland, South Korea, and China. He has served on the panels of NIH, CDC, NIOSH, and

National Academy of Sciences, and has published >425 publications, including eight major

books: (1) Toxicology of Organophosphate and Carbamate Compounds, (2) Veterinary

Toxicology: Basic and Clinical Principles, (3) Handbook of Toxicology of Chemical Warfare

Agents, (4) Anticholinesterase Pesticides: Metabolism, Neurotoxicity and Epidemiology,

(5) Reproductive and Developmental Toxicology, (6) Biomarkers in Toxicology, (7)

Nutraceuticals: Efficacy, Safety and Toxicity, and (8) Nutraceuticals in Veterinary Medicine

(in preparations). In 2006, he received the Murray State University’s Distinguished

Researcher Award; and in 2014, Outstanding Research Award. He is a diplomate of the

American Board of Toxicology, and Fellow of American College of Toxicology, American

College of Nutrition, and Academy of Toxicological Sciences. Currently, he holds active

membership in more than a dozen academic societies, including American College of

Nutrition, American Veterinary Medical Association, American Society for Pharmacology

and Experimental Therapeutics, Society of Toxicology, Eurotox, International Society for the

Study of Xenobiotics, and American College of Toxicology.

rgupta@murraystate.edu

Ramesh C Gupta

Ajay Srivastava

, Rajiv Lall

Murray State University, USA

Vets Plus Inc, USA

Current trends in nutraceuticals with special reference to osteoarthritis