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September 09-10, 2019 | Edinburgh, Scotland
2nd Global Summit on
3rd International Conference on
Dermatology and Cosmetology
Wound Care, Tissue Repair and Regenerative Medicine
Joint Event
&
Journal of Dermatology Research and Skin Care | Volume 3
Dermatol Res Skin Care, Volume 3
High Frequency (20 MHz) Focused Ultrasound - A novel method for medical dermatology
Torsten Bove and Tomasz Zawada, Jørgen Serup
TOOsonix A/S, Denmark
Objective: High intensity focused ultrasound (HIFU) at high
frequencies is not well explored, and commercial systems
with frequencies above 15 MHz for human therapy have
so far not been commercially available. High frequencies
however allow very small focal zones, and thereby precise
confinement of lesions in e.g. the dermis layer of human skin.
The objective of this work is to demonstrate a method and a
newHIFU systemworking at 20MHz suitable for a wide range
of indications in dermatology.
Method: A new 20 MHz HIFU system has been used in the
presented experiments. Tissue mimicking phantoms gel
were used to verify acoustic field distribution and depth of
treatments. The system was used to demonstrate the safety
in a minipig animal study. Human experimental treatments
were performed to investigate the efficacy of the method for
Actinic Keratosis and tattoo removal.
Results: Pre-clinical, animal studies and pilot human clinical
results are presented. Treatment on human skin demonstrate
efficient reduction of Actinic Keratosis as well as removal of
tattoos, regardless of color in a single session. The results
indicate that a protocol for coverage of larger skin areas
in 2 or 3 short sessions is feasible. The encouraging results
demonstrate the feasibility for expanding the method to a
very wide range of indications in the field of dermatology in
the future.
Conclusions: High frequency HIFU has been used for
research-based human treatment. A very effective method
for treatment of Actinic Keratosis and tattoo removal is
demonstrated. The method therefore has the potential to
supplement or replace lasers and/or photodynamic therapy
in both hospital and dermatology clinics.
Speaker Biography
Torsten Bove has nearly 20 years of experience in ultrasound research
and manufacturing. Recently he was managing director at Meggitt A/S, a
positionheheldformorethan10yearsduringaperiodwherethecompany
grew significantly and became one of the world’s leading suppliers of
piezoelectric elements for aerospace andmedical devices. He holds .
inMaterials Science and has business diplomas fromCopenhagen Business
School and Oxford University. He is a LEAN champion, and has extensive
practical experience with management in an international environment.
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