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September 09-10, 2019 | Edinburgh, Scotland
2
nd
Global Summit on
3
rd
International Conference on
Dermatology and Cosmetology
Wound Care, Tissue Repair and Regenerative Medicine
Joint Event
&
Journal of Dermatology Research and Skin Care | Volume 3
Dermatol Res Skin Care, Volume 3
Biocellulose mask as delivery system: Evaluation of quality, safety and effectiveness
Perugini Paola
and
Bleve Mariella
University of Pavia, Italy
B
acterial Cellulose (BC) has become of great interest
in recent years as delivery system in several areas of
application including food, drugs and cosmetics thanks to
exclusive advantages such as: high biocompatibility, water
holding capacity, good gas permeability. Several bioactive
ingredients are currently loaded into bacterial cellulose
masks. However, only a few studies have reported the
effectiveness of such delivery systems. The novel Authors’
approach lead to a protocol for checking quality, safety and
efficacy of Bacterial Cellulose masks. Two non-destructive
techniques, Near-Infrared Spectroscopy (NIR) and Multiple
Light Scattering (MLS) were used to verify different
parameters affecting the quality of masks over time. The
effectiveness on skin parameters of three biocellulose
masks with different cosmetic effects (anti-aging, lifting,
and cell renewal) were evaluated through an “in vivo” study
involved 69 healthy Caucasian female volunteers between
25 and 64 years old. In particular, skin moisturizing, skin
color, skin viscoelastic properties, skin surface smoothness,
wrinkle reduction, dermal homogeneity, and stratum
corneum renewal were evaluated. Erythema Index values
and TEWL values obtained during in vivo tests highlighted
the great tolerability of BC masks: skin’s parameters were
not altered upon continued use, no occlusive effect was
reported, nor the skin barrier function has been affected. A
significant decrease in skin roughness and wrinkle breadth,
and an improvement in dermal homogeneity and firmness,
were observed after two months of treatment with “anti-
aging” masks. A significant improvement in skin firmness
and elasticity was observed after one month of treatment
with “lifting” masks. Furthermore, a one-month treatment
with “cell renewal” masks promoted the production of
new skin cells through a mild exfoliating action. This study
highlights that biocellulose masks are safe and effective
delivery systems to successfully release into the skin several
types of active compounds exerting many beneficial effects.
Speaker Biography
Perugini Paola has completed her PhD in Pharmaceutical Chemistry and
Technology fromUniversity of Pavia, Italy. She is professor at the University
of Pavia and she is the Director of Second DegreeMaster in Cosmetological
Sciences at the University of Pavia. She has over 200 publications that have
been cited over 1730 times, and her publication H-index is 36 and has been
serving as an editorial board member of reputed journals.
e:
paola.perugini@unipv.it