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June 12-13, 2019 | Edinburgh, Scotland
Pediatrics and Clinical Pediatrics
2
nd
World Congress on
Current Pediatric Research | Volume: 23
Haematological profile of Sickle cell anaemia and Thalassaemia from central India
B P URADE
Anthropological Survey of India, India
T
he aim of the present study was to determine the
haematological profile of sickle cell anaemia (SCA) and
thalassaemia (β-Thal) from Central India. Both SCA and
β-Thal are a major public health in the world in general
and India in particular where about 42 million sickle cell
trait (SCT) and about 3.5 million β-Thal carriers live in
India with its predominance in central and southern India.
Haematological tests on 2769 premarital children aged
6-14 years comprising of 2224 controls, 438 carriers for
SCA and 107 carriers for β-thalassaemia were performed.
Low RBC, MCV, Hb, RDW, MCH, and MCHC and high WBC,
MPV, HCT, and platelet dominate the haematological
profile among SCT and β-Thal carriers compared to normal
children. Slightly higher macrocytic cell morphology of
sickle cell anaemia was major concerned. The mean Hb
level among the carriers of sickle cell anaemia (12.82 ±
2.11 g/dl) was adequate but for β-Thal (10.89 ± 1.89) it
was considerably low. Microcytosis and hypochromia
seen by the low mean values of mean corpuscular volume
(MCV) and mean corpuscular haemoglobin (MCH) in the
β-thalassaemia.
e:
druradebp@gmail.comCurrent Pediatric Research, Volume 23
ISSN: 0971-9032