clinical-nursing-pediatrics-2018-scientifictracks

6 / 19

Page 21
Notes:
allied
academies
Current Pediatric Research| Volume: 22
November 28-29, 2018 | Dubai, UAE
15th World Congress on
Pediatrics, Clinical Pediatrics and Nutrition
28th International Conference on
Nursing Practice
Joint Event
&
Orthostatic tolerance and results of Autonomic testing in children with Migraine with and without Aura
Aleksandra Gergont, Sławomir Kroczka and Marek Kaciński
Jagiellonian University, Poland
Background: Symptoms and signs of autonomic nervous system
(ANS) dysfunction and orthostatic intolerance are common in
patients with migraine. Despite the clinical signs of involvement
of ANS in the pathophysiology of migraine, the mechanism
of autonomic dysfunction was not fully explained. One of the
methods to establish a sympatho-vagal balance is examination
low frequency (LF) and high frequency (HF) spectrum of heart
rate variability.
Aims: The aim of the study was to establish LF/ HF ratio in
children with migraine (without and with aura) during an
orthostatic challenge. Prospective research, approved by
Bioethical Commission of Jagiellonian University.
Material and methods: The examination was performed in 86
children with migraine during a headache-free period and in 32
children without headaches and syncope, constituting an age-
matched control group. HRV was evaluated during rest, during
a 10-min 70 degrees head-up passive tilting and during 3-min
active standing test, using Task Force Monitor 3030i/3040i.
Results: In all 47 children with migraine with aura head-up tilt
test was negative for syncope. In 2/39 children with migraine
without aura and in 2 controls head-up tilt-induced syncope
occurred. Postural orthostatic tachycardia syndrome (POTS)
was diagnosed in 4/24 children with migraine with sensory
aura and in 1 child with migraine without aura. Results of LF/
HF ratio did not differ between groups with migraine with aura
and controls, but they were significantly higher in group of 24
children with migraine with sensory aura during tilting.
Conclusions: Predominance of sympathetic nervous system
activity during tilting, as well as more common POTS in patients
with migraine with sensory aura as compared with healthy
volunteers and patients with migraine without aura, indicate
differential autonomic reactivity. In spite of poor orthostatic
tolerance reported by patients with migraine, active standing
did not reveal differences between migraine patients and
healthy volunteers.
Speaker Biography
Aleksandra Gergont is a certified specialist in neurology and child neurology. She has
completed her PhD from the Jagiellonian University in Krakow, Poland which is one of
the oldest Universities in Europe. She is active in teaching and mentoring. In addition to
education, she practices clinical pediatric neurology. She also conducts clinical research
and is focusing upon dysfunction of autonomic nervous system. She directs autonomic
laboratory at the Department of Pediatric Neurology, where she performs cerebrovascular
Doppler examination and head-up tilt tests. Her research interests have been focused
primarily on migraine, syncope and rare diseases, as well as vascular disorders. She is a
member of Polish Child Neurology Association and she holds leadership position in its
regionalbranchinKrakow.SheisalsoamemberofPolishSocietyofClinicalNeurophysiology.
She is not only author and co-author of several publications but also reviewer.
e:
Aleksandra Gergont et al., Pediatrics and Clinical Pediatrics 2018
& Nursing Practice 2018, Volume 22
DOI: 10.4066/0971-9032-C2-005