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May 13-14, 2019 | Prague, Czech Republic
Chemistry and Medicinal Chemistry
9
th
World Congress on
Asian Journal of Biomedical and Pharmaceutical Sciences | Volume 9
ISSN: 2249-622X
Stability and influence of agro-environmental conditions on phenolic compounds
and biological properties of Grape (
Vitis vinifera L
.) stems
Irene Pereira Gouvinhas
CITAB, Portugal
T
he winery industry is one of the most important
industries worldwide, with an economical and social
impact in Europe and specially in northern Portugal. This
socio-economic activity entails large quantities of by-
products generated annually, causing economical and
environmental problems. In a close connection with the
40 years history of investigation on agro-food valorization,
nowadays, a growing interest has wake up on recycling
winery wastes boosted by the more and more reported
putative health-promoting effects. Furthermore, the
continuous emergence of multidrug resistant bacteria
is becoming a huge threat to human, animal and
environmental health (One health approach). Therefore,
the research for new natural antimicrobial compounds
is the most promising alternative to effectively control
multidrug bacterial infections. Hence, qualitative and
quantitative evaluation of polyphenolic extracts of grape
stems as sources of individual phenolic compounds and
their biological activity
in vitro
(radical scavenging power
and antimicrobial activity) were assessed. Grape stems
revealed to be a rich source of phenolic compounds, even
after some months of storage. Furthermore, all extracts
(with andwithout storage) were able to inhibit the bacterial
growth of the Gram-positive bacteria and Gram-negative
bacteria (except E. coli and K. pneumoniae), revealing the
potential inclusion of these bioactive compounds in the
food, cosmetic, and pharmaceutical industry as functional
ingredients. Furthermore, and as expected, it was also
verified a year-to-year variation proved by a significant
increase of these parameters from 2017 to 2018, revealing
the high influence of growing seasons in the phytochemical
composition of these by-products. The antimicrobial
activity determined in these samples demonstrated to be
not severally affected by the climate conditions of each
year of study, however, the high altitude induced generally
a lower activity in the stem samples, results confirmed by
the multivariate analysis.
e
:
igouvinhas@utad.ptAsian J Biomed Pharmaceut Sci, Volume:9
DOI: 10.4066/2249-622X-C2-021