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Page 45
March 25-26, 2019 | Amsterdam, Netherlands
CARDIOLOGY
AND CARDIAC NURSING
3rd World Congress on
Cardiology Summit 2019 Journal of Cardiovascular Medicine and Therapeutics | Volume 3
OF EXCELLENCE
IN INTERNATIONAL
MEETINGS
YEARS
Note:
PERCUTANEOUS CLOSURE OF PATENT FORAME OVALE (PFO): THE NEW
SUTURE-MEDIATED SYSTEMVS. OLDER SYSTEMS
Anca Irina Corciu
IRCCS Policlinico San Donato, Italy
In patients with paradoxical embolism through a Patent Foramen Ovale (PFO) who are at increased risk of re-
current thromboembolic events, transcatheter closure of the atrial communication represents a more effective
therapy than prolongedmedical treatment. Indeed, percutaneous PFO closure was shown to be safe and feasible
with several prosthetic implantable occluder devices implementing different technologies based on an umbrel-
la-like double disc design. Despite the efficacy of PFO occluder devices, their use has a potential risk of early and
late complications including, in extreme cases, device dislodgement, atrial wall erosion, perforation, fracture,
migration-embolisation, infection, thrombosis, induction of arrhythmias and even death. Additionally, the in-
teratrial septum encumbrance of the prosthetic device may hinder future transseptal puncture and left-sided
interventions such as left atrial appendage closure, arrhythmia ablation and mitral valve interventions. Finally,
risk of allergic reactions to nickel mesh cannot be excluded, and the necessity of prolonged dual antiplatelet
therapy after the procedure might not be tolerated by all patients. Hence, a strategy of percutaneous PFO clo-
sure without a permanently implanted device represents an intuitive and revolutionary technique overcoming
most of the limitations of traditional PFO occluders. Recently, a new percutaneous “deviceless” system based on
surgical suture-mediated PFO closure (NobleStitch EL system) has been introduced in interventional practice.
Early results indicate that the new system is feasible in the majority of septal anatomies, and provides an effective
closure of PFO comparable to traditional devices with a good safety profile at medium-term follow-up.
Anca Irina Corciu, J Cardiovasc Med Ther 2019, Volume 3
Anca Irina Corciu graduated from School in Medicine and Surgery in Cluj Napoca, Romania, and completed her PhD at
Scuola Superiore Sant’Anna, Pisa, Italy. She is working in the department of clinical and interventional cardiology from
Policlinico San Donato, Milan, Italy, as an expert in echocardiography, as well as in Cath Lab. She is directly involved in
multiple research studies, with many participations at national and international conferences as speaker, and published
papers in peer reviewed journals.
BIOGRAPHY