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Page 33
March 25-26, 2019 | Amsterdam, Netherlands
CARDIOLOGY
AND CARDIAC NURSING
3rd World Congress on
Cardiology Summit 2019 Journal of Cardiovascular Medicine and Therapeutics | Volume 3
OF EXCELLENCE
IN INTERNATIONAL
MEETINGS
YEARS
Note:
HYPOTHERMIA AND BLOOD LACTATE DURING CARDIOPULMONARY BYPASS
IN PEDIATRIC PATIENTS
Saeed Taiyari1, Zia Totonchi2, Pouya Farokhnezhad Afshar3 and Sara Taiyari3
1Tehran University of Medical Sciences, Iran
2Shahid Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Iran
3University of Social Welfare and Rehabilitation Sciences, Iran
Introduction: Hypothermic perfusion is widely used in pediatric cardiac surgery units. The present study evalu-
ated the effect of hypothermia severity on serum levels of lactate during Cardio Pulmonary Bypass (CPB) in the
surgical repair of congenital heart defects in children.
Methods: 185 pediatric patients’ candidate for the elective surgical repair for congenital heart disease were
recruited. The patients’ arterial serum lactate, central venous pressure, diuresis, glucose and arterial blood gases
were measured and recorded in four time points including before the CPB, when cooling the patient, when
warming the patient, after the CPB and upon admission to the intensive care unit (ICU).
Results: The mean age of the patients was 28.1 ± 19.6 months. Lactate level significantly raised more quickly in
the patients with hypothermia < 30 compared to in those with hypothermia ≥ 30 (P < 0.001). These two groups
were significantly different in duration of CPB (P < 0.001), duration of cross-clamping (P < 0.001) and volume of
blood filtered (P < 0.001). No statistically significant differences in the volume of the red blood cell (RBC) trans-
fused was observed between two groups (P = 0.12).
Conclusions: Deep hypothermia is associated with higher blood lactate levels which may be associated with
poor outcomes during and after CPB. It is recommended normothermia or mild hypothermia to be used during
CPB in paediatrics. When using deep hypothermia is inevitable, patients are better to be strictly monitored and
screened for adverse outcomes associated with hyperlactatemia.
Saeed Taiyari et al., J Cardiovasc Med Ther 2019, Volume 3
Saeed Taiyari has completed his MSc in critical care nursing and clinical perfusion in cardiac surgery fromTehran Univer-
sity of Medical Sciences. He has been as one of the main writers of some researches which mostly are at publication in
high impact journals. He is senior perfusionist in congenital tertiary at Children Medical Center and is also collaborating
with some research centers located at the hospital.
BIOGRAPHY