biomaterials-materials-physics-2019-keynote

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May 20-21, 2019 | Vienna, Austria
Biomaterials and Nanomaterials &
Materials Physics and Materials Science
2nd International Conference on
Page 46
Journal of Materials Science and Nanotechnology | Volume 3
The need for low-cost, scalable, and dispersion-
processable nanomaterials is a leading motivation for
extensive research in the field of nanocomposite synthesis.
Nowadays, nanomaterials based on biopolymers and
metal nanoparticles have attracted considerable attention
not only in medicine but as well in many other fields
such as catalysis, optoelectronics, information storage,
environmental technology, engineering, etc. Furthermore,
the use of Ag, Au and Cu nanoparticles (NPs) is a cause of
intensive recent research due to excellent properties of
these metals (e.g. good thermal and electrical conductivity,
which might be used in electronics, or optical properties,
which might be exploited in catalysis, diagnostics, sensing,
and therapeutic applications). What is noteworthy, since
multidrug-resistant microorganisms are a major problem
for current medicine, nanoscale materials bring also new
possibilities in the development of effective antimicrobial
systems. Herein, the synthesis of materials based on Ag,
Au, Cu NPs and chitosan with the careful analysis in terms
of physicochemical properties and biological activity in
vitro will be presented. In detail, the chemical structure,
size, and morphology of metal NPs in the chitosan matrix
have been studied by scanning electron microscopy
(SEM), scanning transmission electron microscopy with
energy-dispersive X-ray analysis (STEM-EDX) and powder
X-ray diffraction (XRD). The surface oxidation state of the
metallic nanoparticles and elemental analysis by depth
profiling have also been evaluated by X-ray photoelectron
spectroscopy (XPS). FTIR measurements were carried
out to identify possible interactions between metal
nanoparticles and chitosan molecules. Antibacterial
activity was evaluated according to the European Norm
ASTM E2180-07 for polymeric materials, against selected,
resistant Gram-(+) and (-) bacterial strains (S. aureus and P
aeruginosa, respectively). The cytotoxicity of the selected
nanocomposites was also evaluated using two human
cell lines: A549 (human lung adenocarcinoma epithelial
cell line) and HaCaT (an immortal human keratinocyte).
In view of the potential biomedical application, the most
promising materials in form of colloids, films, and coatings
will be pointed out.
Speaker Biography
Agnieszka Kyziol has completed her PhD at the age of 29 years from
Jagiellonian University, Kraków, Poland. She is the assistant professor
in Coordination and Bioinorganic Physiochemistry Group at faculty of
chemistry of Jagiellonian University. She has over 60 publications that
have been cited over 800 times, and her publication H-index is 15 and
has been serving as an editorial board member of reputed Journals.
e:
Agnieszka Kyziol
Jagiellonian University, Poland
Novelties in bactericidal nanocomposites based on biopolymers and
metal nanoparticles
Notes: