biomaterials-materials-physics-2019-keynote

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May 20-21, 2019 | Vienna, Austria
Biomaterials and Nanomaterials &
Materials Physics and Materials Science
2nd International Conference on
Page 40
Journal of Materials Science and Nanotechnology | Volume 3
Sou Ryuzaki
Kyushu University, Japan
Nanopore devices for nano-biomedical
Rapid structural analysis methods for biomolecules and
biomaterials consisting of single or several molecules
in solution represent innovative technologies to reveal
their functions because the functions strongly depend on
their own structures. However, there presently exist no
rapid structural analysis methods for single nanomaterials
suspended in liquid environment. Nanopore sensors have
been widely used to investigate the volume of particles and
molecules passing through the pore by probing temporal
changes in the ionic current pulses. These pulse sensors
have been developed for not only size but also shape of
analyte during recent years. Smaller aspect ratio defined
as the ratio of the depth to the diameter and a high-speed
current detection systemprovide greater spatial resolution,
i.e. tomograms of a material passing through a nanopore.
Here we will report the development of low-aspect-ratio
nanopores with a spatial resolution of ca.35.5 nm and
the 10 MHz-current-amplifier, resulting in realization of
ultrafast time resolutions of 1.0 μs for the tomography
analysis of a material passing through a nanopore.
Combining state-of-the-art technologies with Multiphysics
simulation methods to translate ionic current data into
tomograms of nanomaterials passing through a nanopore,
we have achieved rapid structural analysis of single and
dabble polystyrene (Pst) beads, and bionanomaterials
such as E-colis in aqueous solutions [1]. In addition, we
will also report plasmonic nanopore devices, which enable
us to detect Surface-enhanced Raman Spectrum of a
material inside a nanopore. The nanopore devices will be
innovative technologies for the fields of Nano biodevices
and structural biology.
Speaker Biography
Sou Ryuzaki is currently an assistant professor of Institute for Materials
Chemistry and Engineering (IMCE) at Kyushu University. He graduated
with his PhD from department of nuclear engineering at Tokyo Institute
of Technology in March 2010. After receiving his PhD, he worked for
Nano-Science Center of University of Copenhagen as a postdoctoral
research fellow (2010–2011), and he was an assistant professor of
Institute of Scientific and Industrial Research (ISIR) at Osaka University
(2012–2014). He is engaged in researches related to fundamental
materials physics (nanocarbons), plasmonics (plasmonic lasers), organic
devices (photovoltaic cells), and nano biodevices (nanopore devices).
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