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J Parasit Dis Diagn Ther 2017 | Volume 2 Issue 4
allied
academies
International Conference on
Zoology, Microbiology & Medical Parasitology
October 30-November 01, 2017 | Chicago, USA
Statement of the Problem: Malaria is a public health problem
in tropical and subtropical regions of the world. In most
Mexican territory, P. vivax transmission has been historical and
remains in some malarious foci along the pacific coast and in
the southern region, while P. falciparum was eliminated about
eight years ago. In order to contribute to malaria control and
elimination in the region, in southern Mexico we carried out
several studies to discover vector and parasite factors involve
in the P. vivax transmission. The purpose of this study was to
investigate P. vivax genetic variation, and vector susceptibility,
to identify vector-parasite factors favoring P. vivax transmission.
Methodology & Theoretical Orientation: The most abundant
Anopheline vector species of different sites from Mexico were
inbred under insectary conditions. P. vivax infected blood
obtained from patients living in southern Mexico was used to
test the mosquito susceptibility. The number of mosquitoes
infected with oocyst and the number of oocysts per mosquito
were recorded per colony and per mosquito species. Parasite
genotype was determined and its association to vector
susceptibility was analyzed.
Findings: The data exposed different P. vivax genotypes in
southern Mexico that produced different degree of oocyst
infection in An. albimanus and/or An. pseudopunctipennis,
and An. punctipennis. Moreover, there were different colonies
of two Anopheline species from distant geographic sites that
showed similar susceptibility to southern parasites.
Conclusion & Significance: The finding suggests that P. vivax in
southern Mexico comprises strains with different compatibility
to the local Anopheline species. These mosquito vectors are
distributed across the country and likely capable to sustain
malaria transmission. On the other hand, the genetic pool of
malaria parasites seem reduced to few genotypes, those more
adapted to local vector species.
Speaker Biography
Lilia Gonzalez-Ceron, PhD. Parasitologist. Principal researcher of the Regional Centre
of Research in Public Health, National Institute of Public Health, Chiapas, Mexico.
She has been working with P. vivax malaria since 1986s, and has been involved in
epidemiological studies, vector-parasite interactions, diagnosis and treatment. Also,
she is interested in the evolutionary genetics of P. vivax in Mexico and its transmission
dynamics.
e:
Lilia Gonzalez-Ceron
Regional Center for Research in Public Health, Mexico
Deciphering the participation of Anopheline species in the transmission of
Plasmodium vivax in Mexico