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Archives of Industrial Biotechnology | Volume 2

May 14-15, 2018 | Montreal, Canada

World Yeast Congress

ging is a physiological process caused by time-dependent,

progressive changes in multiple biological systems,

which induces the increased incidence of age-related

diseases. Among anti-aging strategies, calorie restriction

(CR) is a widely accepted anti-aging paradigm. Recently,

high-throughput technologies are applied to find aging/

CR-associated genes. Given that high-throughput methods

generate huge amounts of data, it is necessary to study how

these CR-related bio-molecules work, interact, and exert

their influence in terms of systemic view. Here, we propose

database of aging and calorie restriction (CR) related genes.

We first screened mouse genes that are related to both

aging and CR. We then investigated the orthologs of the

common genes in yeast and used these results to confirm

and measure functions and life-spans using yeast knockout

strains. We suggested a systematic framework and database

for further understanding of aging process.

Speaker Biography

Hae Young Chung has completed his PhD at the age of 30 years from Toyama University

and postdoctoral study from University of Texas Health Science Center at San Antonio.

He is the director of Molecular Inflammation Research Center for Aging Intervention.

He has published more than 400 papers in reputed journals and has been serving as an

editorial board member of AGE.

Study on Yeast Lifespan for Aging- and Calorie Restriction- related Genes

Hyoung-Sam Heo

and

Hae Young Chung

Korea National Institute of Health, Republic of Korea

Pusan National University, Republic of Korea