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Journal of Clinical and Experimental Toxicology | Volume: 2
December 03-04, 2018 | Dubai, UAE
International Conference on
6
th
International Conference on
Toxicology, Clinical Toxicology & Pharmacology
Recycling & Waste Management
Joint Event
&
Deltamethrin induced changes in endocrine glands regulating Calcium & Ionic balance in
Heteropneustes fossilis
Prem Singh Bugasara
SBRM Government College, India
T
he impact of deltamethrin on the freshwater fish
Heteropneustes fossilis
exposed to two sub lethal
concentrations (0.09 mg/L and 0.18 mg/L) for 30 days on the
activities of endocrine glands viz. prolactin gland, corpuscles of
stannous and ultimobranchial gland. Changes in the structure
of endocrine gland lead significant variation in inorganic ions
concentration Na
+
, K
+
, Ca
2+
and Mg
2+
in brain, kidney, gills and
intestine of
H. fossilis.
Ca
2+
/ Mg
2+
ATPase activities significantly
decreased in all vital tissues viz., brain, gills, intestine and
kidney at both the exposure for 30 days in
H. fossilis
. The
ultimobranchial gland exhibited mild histological changes at
lower concentration of deltamethrin. At higher concentration
decrease in staining response of the cytoplasm, decrease in
nuclear volume and degeneration in the cells were noticed. In
corpuscle of stannous sever changes observed with increase in
granulation, vacuolation and degeneration of cell membrane
noticed at higher concentration of deltamethrin. In prolactin
cells sever changes observed at both the concentration for 30
days exposure. Significant changes observed in ionic balance in
vital tissues brain > gill> intestine > kidney of the fish exposed
to higher concentration of deltamethrin. Significant changes
noticedinthevitalorgansviz. Ioniclevelsinbrain,gills,kidneyand
intestine. During exposure of deltamethrin endocrine glands,
brain and intestine found to bemost affected tissues of the fish.
Speaker Biography
Prem Singh Bugasara is working as a associate professor, department of zoology, Shri
Baldev Ram Mirdha Government College, Nagaur, Rajasthan. He has been associated
with profession for 16 years. He was awarded Ph.D degree from Maharaja Ganga Singh
University, Bikaner for research work on blackbucks. He is passionately engaged in
biodiversity conservation and has conducted several seminars and awareness programs
to encourage people to protect native flora and fauna. He always tries to improve society
and youth by discussing various social issues. He has completed a research project on
wildlife conservation and assessment of biodiversity in Rotu Conservation Reserve, Nagaur
(Rajasthan)in year 2016-17 and is continuing with another wildlife research project. He
has published research papers on various topics in national and international journal.
e:
prembugasara@gmail.comPrem Singh Bugasara
, Toxicology 2018 & Recycling 2018, Volume 2
DOI: 10.4066/2630-4570-C1-002