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Biomedical Research (An International Journal of Medical Sciences) | ISSN: 0976-1683 Volume 30
June 06-07, 2019 | London, UK
2nd International Conference on
Tissue Science and Molecular Biology,
Stem Cells & Separation Techniques
Joint Event
The world advancing rapidly in the field of technology,
a simple example is our mobile phone. However, when
compared to healthcare, the diagnostic and treatment of
diseases are still very poor and surgery has not changed
significantly compared with 50 years ago. There is plenty
of news in academia/media that everything could be
diagnosed and cured, but in reality, the invention has
been tested in rodents and has not moved to human. This
is due to the complexity of the medical devices builds in
university research environment, the lack of difficulty
taking devices to clinical setting, as well as the positive
outcome obtained from in vitro and rodents may not
transferable to human. Therefore, need going back to
the drawing table and rethink to build medical devices
that; commercially feasible, reliable, sensitive, repeatable
and non-toxic and biocompatible. The potential for using
smart nanomaterial and consequent research to replace
damaged tissues has also seen a quantum leap in the last
decade. In 2010, two scientists in the UK realized they had
isolated a single layer of carbon atoms on a scotch tape.
Since then, graphene has captured the imagination of
researchers due to its fascinating properties. Graphene
considers as a wonder material, it is the strongest material
on the planet, an order of 200 times stronger than steel,
super-elastic and conductive. Graphene's carbon atoms
are arranged into hexagons, forming a honeycomb-like
lattice. The functionalised graphene oxide (FGO) with
polyhedral oligomeric silsesquioxane (POSS) from butterfly
wing are nontoxic and antibacterial. FGO has been used
for drug and gene delivery, development of biosensor
or in nanocomposite materials development of human
organs. In my talk, I present and discuss our work on
the application of FGO-POSS in development of medical
sensors, drug, gene and stem cells delivery, as well as the
development of human organs with stem cells technology.
The materials can be fabricated to human organs with the
3D printer or other fabrication methodologies. The scaffold
from these materials is functionalised with bioactive
molecules and stem cells technology for the development
of human organs. The data for the development of organs
using these materials will be presented. In conclusion, the
graphene, POSS bring new hope for gene, drug and stem
cells delivery for repair and replacement of organs.
Speaker Biography
Alexander Seifalian, professor of nanotechnology and regenerative
medicine,workedattheRoyalFreeHospitalandUniversityCollegeLondon
for over 26 years, during this time he spent a period of time at Harvard
Medical School looking at the cause of cardiovascular diseases and a year
at Johns Hopkins Medical School looking at the treatment of liver. He
published more than 647 peer-reviewed research papers and registered
14 UK and international patents. He is currently CEO of NanoRegMed Ltd,
working on the commercialization of his research. During his career, he
has led and managed many large projects with successful outcomes in
terms of commercialization and translation to patients. In 2007, he was
awarded the top prize in the field for the development of nanomaterials
and technologies for cardiovascular implants by medical future innovation
and in 2009, he received a Business Innovation Award from UK Trade &
Investment (UKTI). He was the European Life Science Awards’ winner of
most innovative new product 2012 for the “synthetic trachea”. He won the
Nanosmat Prize in 2013 and in 2016, he received the distinguish research
award in recognition of his outstanding work in regenerative medicine
from Heals Healthy Life Extension Society. His achievements include
the development of the world first synthetic trachea, lacrimal drainage
conduit and vascular bypass graft using nanocomposite materials,
bioactive molecules and stem cell technology. He has over 15,000 media
report from his achievement, include BBC, ITV, WSJ, CNN and many more.
Currently, he is working on the development and commercialization of
human organs using graphene-based nanocomposite materials and stem
cells technology.
e:
Alexander Seifalian
NanoRegMed Ltd, UK
Graphene, butterfly and stem cells is set to revolutionise medical
devices
Alexander Seifalian, Biomed Res, Volume 30
ISSN: 0976-1683