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May 20-21, 2019 | Rome, Italy
Journal of Cell Science and Mutation | Volume 3
OF EXCELLENCE
IN INTERNATIONAL
MEETINGS
YEARS
Stem Cell Congress 2019
STEM CELLS AND REGENERATIVE MEDICINE
2nd International Conference on
PROMISING FUTURE OF STEM CELLS-BASED TREATMENTS IN REPRODUCTIVE MEDI-
CINE: IN HOUSE EXPERIENCE OF IVF CLINIC
Nayana Patel
Akanksha Hospital and Research Institute, India
S tem cells-based therapy has emerged as one of the most promising approaches for the management of
various intractable disorders. Recently the role of adult autologous stem cells has showed its effectiveness
in many chronic and incurable diseases such as myocardial infraction, cancer and Type II diabetes. However,
compared to the above chronic conditions, the role of stem cells in reproductive disorders such as azoosper-
mia, endometriosis and ovarian failure remains largely unexplored. Some studies have shown a potential role
of bone marrow derived stem cells (BMSCs) in reproductive medicine. Our studies on bone marrow derived
stem cells as bone marrow concentrate (BMCs) for the treatment of ovarian rejuvenation, testicular rejuve-
nation and thin endometrium lining regeneration have shown its potential in improving these conditions.
For example, author found that the application of BMCs improved the testicular functioning in terms of total
number of sperm its motility and the quantity of semen in patients with severe azoospermia, thus showing
its potential in spermatogenesis. Furthermore, BMCs with platelet rich plasma (PRP) improved the lining of
endometrium in patients with thin endometrium. What’s more, it has helped in the implantation of embryos
in patients having recurrent implantation failure. Finally, they discovered that ovarian rejuvenation with BMCs
also improved the total number of eggs and its quality. All together, these results indirectly demonstrated the
potential of these cells in treatment of various fertility related conditions. These studies, although promising,
should be considered preliminary and they need more research, involving clinical trials to fully evaluate BMCs
role in reproductive medicine.
Nayana Patel, Adv Cell Sci Mut. 2019, Volume 3
Nayana Patel is a Medical Director of Akanksha Hospital and Research institute, India. She is considered as pioneer in the field of IVF
and surrogacy in India. Her fertility clinic have helped in deliver of total 1195 surrogate babies to national and international couples
till date.
BIOGRAPHY