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Virology research J 2017 Vol 1 Issue 2

Page 14

Notes:

July 26-27, 2017 | Vancouver, Canada

WORLD CONFERENCE ON STDs, STIs & HIV/AIDS

allied

academies

I

ncreased availability of one pill-once daily antiretroviral

therapy (ART) combinations with greater potency and

tolerability has created a dynamic shift in prescribing

patterns towards simplification to these newer therapies.

In this presentation, we will identify common one pill-once

daily ART combinations and most current recommendations

for treatment of HIV. In an era of ART simplification

encouraged by an armamentarium of better therapies,

the HIV aging population is increasing. Given these trends,

the prevalence of comorbidities is also increasing in the

HIV aging population. One example includes the large HIV

Dutch ATHENA cohort projecting a significantly increased

prevalence in both the number of comorbidities (especially,

cardiovascular disease) and concomitant medications used

to treat these comorbidities by 2030. Consequences of

polypharmacy include increased pill burden, costs, drug-drug

interactions, and adverse effects. In this presentation we will

briefly discuss current and future polypharmacy trends in an

aging HIV population. Studies show that adherence to ART

is improved if HIV patients are taking fewer medications

on a daily basis. Although many strategies exist to reduce

polypharmacy to ensure sustainable success on ART, one

excellent measure may include precision medicine. In this

presentation, we will describe specific examples of how

using this personalized healthcare approach can serve

importantly in guiding choices in both ART and management

of common comorbidities in the HIV aging population.

Finally, we will conclude with factors affecting clinical uptake

of pharmacogenetic testing and discuss future implications.

Speaker Biography

Dr. Crutchley graduated from Duke University in 2001. He then received his doctorate

of Pharmacy from the University of North Carolina at Chapel Hill. Dr. Crutchley contin-

ued his education further by completing his PGY-1 Pharmacy Practice Residency at the

University of Texas at Tyler and his PGY-2 HIV Specialty Residency at the State Universi-

ty of New York at Buffalo. Since then, he has also completed a STAR Health Disparities

Fellowship through the University at North Texas Health Science Center at Fort Worth.

Dr. Crutchley is currently working as a Clinical Associate Professor at the University of

Houston, College of Pharmacy. He works as a HIV clinical pharmacist at Therapeutic

Concepts (private adult HIV clinic) and the Retrovirology Clinic at Texas Children’s Hos-

pital with HIV-infected children and adolescents. Dr. Crutchley established a new and

innovative PGY-2 HIV Ambulatory Care/Clinical Pharmacogenetics Residency Program

at the University of Houston. His research interests include complimentary alternative

medicine and pharmacogenetic approaches used to improve the quality of life and

lifespan of HIV-infected patients.

e:

rdcrutchley@uh.edu

Rustin Crutchley

University of Houston, USA

Precision medicine in the HIV aging population