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Virology Research Journal | Volume 2
allied
academies
May 18-19, 2018 | Montreal, Canada
2
nd
World Conference on
STDs, STIs & HIV/AIDS
T
here are some evidences regarding beneficial effects
of carnitine in improvement of depression symptoms.
Incidence of depression is significantly higher among HIV
positive individuals compared to HIV negative populations.
Also carnitine deficiency is prevalent in HIV positive
individuals. In a cross-sectional study correlation between
serum carnitine level and depression severity based on the
Beck Depression Inventory questionnaire was assessed in
100 HIV/AIDS (42 males and 58 females) patients. According
to the Beck Depression Inventory definitions, 31%, 16%, and
21% of the patients experienced mild, moderate, and severe
depression, respectively. Themean ± SD serumconcentration
of total carnitine in the patients was 37.96 ± 26.08 (µmol/L).
Fifty-four (54%) patients were categorized as carnitine
deficient. A non-statistically significant negative correlation
between patient’s depression scores and total levels of
serum carnitine was found. Considering the prevalence of
depression among HIV/AIDS patients and probable role of
carnitine in the pathogenesis of depressive disorders, more
studies are needed to reveal correlation between depression
and the body storage of carnitine.
e:
z_kh14@yahoo.comFrequency of depression and its correlation with serum carnitine level in HIV/AIDS patients
Khazaeipour Z
Tehran University of Medical Sciences, Iran