spine-addiction-2018-posters-abstracts

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Journal of Neurology and Neurorehabilitation Research | Volume 3

November 26-27, 2018 | Dubai, UAE

Spine and Spine Disorders

Addiction Research and Therapy

3rd International Conference on

International Conference on

Joint Event

Cervical spine and cord angle mismatch in the pathogenesis of myelopathy

Tomasz Tykocki

and

Guy Wynne-Jones

Royal Victoria Infirmary Newcastle upon Tyne Hospital, UK

Background:

Cervical Myelopathy is a complex pathology and

dynamic compression of the tethered cervical cord, which may

be responsible for clinical symptoms.

Methods:

Patients with Cervical Canal Stenosis who had

magnetic resonance imaging in flexion and extension positions

were retrospectively reviewed. All cases were evaluated in

Nurick grade. The cervical parameters-Cervical Cord (CC)

angle, Cervical Lordosis, and Spine/Cord (S/C) angle ratio-were

measured on the magnetic resonance imaging. Mean values of

these parameters were compared between non-myelopathic

(Nurick grade 0) and myelopathic groups (Nurick grades 1-5).

A multinomial ordinal logistic regression was used to predict

outcome for Nurick grade using the CC angle, the cervical

lordosis angle, and the S/C angle ratio as independent variables.

Results:

Atotalof65patients(35men)withthemeanageof58.6

± 11.4 years were analyzed. A comparison of means between

Nurick grade 0 against each of myelopathic grades 1-5 revealed

significant differences only for the S/C angle ratio. A cumulative

comparison between non-myelopathic and myelopathic grades

for the S/C angle ratio showed significant difference of 0.29

(1.16 ± 0.5 vs. 1.45 ± 0.6, respectively; P < 0.05). Cumulative

comparison for the CC angle difference in flexion and extension

lordosis did not show substantial differences. The S/C angle

ratio was the only significant parameter in the prediction of

the Nurick grade with an odds ratio of 2.63 (95% confidence

interval 2.11-2.79).

Conclusions:

A positive correlation between Nurick grade and

cervical spine and cord angle mismatch was found.