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allied
academies
August 16-17, 2018 | Paris, France
Primary Healthcare
12
th
International Conference on
International Conference and Medicare Expo on
&
Pediatrics Health Care
Joint Event
Journal of Current Pediatric Research | Volume: 22
Aim:
Theaimthis trialwas observational clinical thenewborns
with diagnosis of Hypoxic Ischemic Encephalopathy treated
with hypothermia therapy in use of the Neonatal Laminar
flow unit1.
Methods:
We involved 53 newborns in this trial, all born in
the hospital itself, newborns at up to 35 weeks of gestation,
with up to 6 hours of life. Total body cooling was achieved
using the neonatal laminar flow unit for 72 hours, with
continuous rectal temperature servo control, isolation and
humidification. Outcome measures were cerebral palsy, a
Bayley II Mental Development Index score <70, hearing loss
or blindness. We compared findings with our previously
published studies2 and two meta-analyses3,4.
Results:
We included 53 newborn infants (73% male) with a
birthweight of
3.562± 1548 g and gestational age of 38 ±3.4 weeks. We have
used to categorize the diagnosis of the Hypoxic Ischemic
Encephalopathy, the Siben Neurologic Score 5 associated
the Sarnat Score6; the most of the newborns( 73%) had
Siben’s score three points or more to serious HIE confirmed
by Sarnat Score and 27% had Siben’s score three points or
more to moderate HIE confirmed by Sarnat Score.
Total body cooling (33–34°C) was achieved in 75 minutes
and maintained with servo control. At 18–24 months of age,
five of the 38 survivors were diagnosed with cerebral palsy,
two was diagnosed with blindness and one with impaired
hearing.
Conclusion:
The use of the Neonatal laminar flow unit to
supply total body hypothermia therapy in newborns with HIE
was effective and our results were similar our previously trial
and two meta-analyses.
e:
joseperezneo@gmail.com53 Newborns with Hypoxic Ischemic Encephalopathy treated with Hypothermia therapy using Neonatal
Laminar Flow Unit
Jose M R Perez
Casa de Saúde de Guarulhos and Stella Maris Hospital-Guarulhos-SP, Brazil
Pediatrics & Primary HealthCare 2018, Volume 22
DOI: 10.4066/0971-9032-C1-003