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Page 49

April 17-18, 2019 | Frankfurt, Germany

Parkinson’s, Huntington’s & Movement Disorders

International Conference on

Journal of Brain and Neurology | Volume 3

Analysis of Sleep Macrostructure in patients diagnosed with Parkinson’s disease

Justa Elizabeth González-Naranjo

International Center for Neurological Restoration, Cuba

P

atients diagnosed with Parkinson’s disease

present sleep disorders with a higher frequency

than the general population. The sleep architecture

in these patients shows variations with respect

to the normal population, so in this work it was

decided to investigate the characteristics of the

macroarchitecture of sleep in patients diagnosed

with Parkinson’s disease. A polysomnographic study

was carried out on 77 patients diagnosed with

Parkinson’s disease. All the studies were processed

according to the AASM Manual for the Scoring of

Sleep and Associated Events v.2.2, and to the criteria

of the International Classification of Sleep Disorders

3rd ed. (2014). Processing was carried out using

descriptive statistics, as well as non-parametric

analysis for comparison between cases and controls.

The group of patients showed significant reductions

of theN2, N3, andREMsleep stageswhen compared

with a control group, as well as a significant increase

in intra-sleep wakefulness. The number of REM–

NoREM sleep cycles and sleep efficiency showed

marked reduction compared to the control group.

There was a statistically significant difference in

the macroarchitecture of sleep between patients

diagnosed with Parkinson’s disease and healthy

controls.

e

:

egonzalez@neuro.ciren.cu