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Page 49
April 17-18, 2019 | Frankfurt, Germany
Parkinson’s, Huntington’s & Movement Disorders
International Conference on
Journal of Brain and Neurology | Volume 3
Analysis of Sleep Macrostructure in patients diagnosed with Parkinson’s disease
Justa Elizabeth González-Naranjo
International Center for Neurological Restoration, Cuba
P
atients diagnosed with Parkinson’s disease
present sleep disorders with a higher frequency
than the general population. The sleep architecture
in these patients shows variations with respect
to the normal population, so in this work it was
decided to investigate the characteristics of the
macroarchitecture of sleep in patients diagnosed
with Parkinson’s disease. A polysomnographic study
was carried out on 77 patients diagnosed with
Parkinson’s disease. All the studies were processed
according to the AASM Manual for the Scoring of
Sleep and Associated Events v.2.2, and to the criteria
of the International Classification of Sleep Disorders
3rd ed. (2014). Processing was carried out using
descriptive statistics, as well as non-parametric
analysis for comparison between cases and controls.
The group of patients showed significant reductions
of theN2, N3, andREMsleep stageswhen compared
with a control group, as well as a significant increase
in intra-sleep wakefulness. The number of REM–
NoREM sleep cycles and sleep efficiency showed
marked reduction compared to the control group.
There was a statistically significant difference in
the macroarchitecture of sleep between patients
diagnosed with Parkinson’s disease and healthy
controls.
e
:
egonzalez@neuro.ciren.cu