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academies
February 18-19, 2019 | Paris, France
Joint Event
Green Chemistry and Technology
8
th
World Congress on
International Conference on
Organic and Inorganic Chemistry
Journal of Industrial and Environmental Chemistry| Volume: 3
Biomaterials as targeted tool for medical applications
Amany A Mostafa
National Research Centre, Egypt
O
ver the past decades, biomaterials play an important
role in the field of medicine and health care. The use
of synthetic biomaterials has extensive progress due to
chronic diseases, malfunction, traumatic accendients and
surgical reconstruction. Many research works have been
focused on biomaterials in the field of tissue engineering,
drug delivery besides imaging as a diagnostic tool. Targeted
delivery of drug incorporated nanoparticles as well as 3D
scaffolds will enhance the efficacy of the anticancer or
other organ-targeted drugs but also reduce the unwanted
toxicity of the drug. Our team developed some promising
nanobiomaterials and nanohybrids for the improvement
of physical, mechanical and cell-biomaterial interactions
beside controlling the targetting drug release. Different
techniques have been used to prepare nanobiomaterials
that help in improving the human life. New formula
incorporated these nanoparticles with an antiinflammatory
drug is used for the nonsurgical treatment of preapical
lesion arisng trauma or bacterial infection as an innovative
tool. Kinetic approach has been used to asses the in vitro
bioactivity of differnt nanocomposites formulae used in
bone regeneration. Other work aimed to the use of cationic
bPEI capped AuNPs for intracellular siRNA delivery that
targeted c-Myc gene in human hepatocellular carcinoma
cells. Material for imaging such as quatum dots stabilized
with magnetic nanopaticles or carbon dots are also benifiial.
A multidisciplenary team has been involved in these work
activities. Herein, I will present and discuss different
laboratoy’s research advancement for medical applications.
e:
amani.mostafa@gmail.comJ Ind Environ Chem 2019, Volume 3
DOI: 10.4066/2591-7331-C1-009